Hypobicarbonatemia, or a reduced bicarbonate concentration in plasma, is a finding seen in
3 acid-base disorders: metabolic acidosis, chronic respiratory alkalosis and mixed metabolic …

The anion gap (AG) measurement is a very useful tool in the evaluation of patients with acid–
base disorders. Once metabolic acidosis is identified, AG will provide the important first step …

In part one of this review (I), we analyzed the changes in acid-base balance induced by
dialysis and showed that the range of normal values depends on the mode of dialysis …

The common approach to the differential diagnosis of metabolic acidosis is to divide the
patients into two catego ries based on whether the anion gap in plasma is increased or not …

Acidosis and nutrition. In recent years there has been increasing evidence for the
deleterious effect of acidosis on a number of fundamental systems of the body including …

Metabolic acidosis is defined as a pathologic process that, when unopposed, increases the
concentration of hydrogen ions (H+) in the body and reduces the bicarbonate (HCO3-) …

The novel hypothesis proposed in this article is that the rise in the anion gap in plasma may.
at times, reflect anions with a volume of distribution that is restricted to the intravascular …

Mixed metabolic—respiratory acid-base disorders may be diagnosed when the respiratory
compensation for a primary metabolic acidosis or alkalosis is inappropriate or when there is …

Because the anion gap is useful in classifying acid-base disorders, quantitative information
on this variable should be readily available. Three populations were studied and means and …

The final diagnosis of acid-base perturbations relies on laboratory analyses. The major
direct tools of assessment are arterial pH and PCO2 and serum electrolytes. From these …