MicroRNA profiling in pediatric acute lymphoblastic leukemia: novel prognostic tools

N Mosakhani, VK Sarhadi, A Usvasalo… - Leukemia & …, 2012 - Taylor & Francis
Childhood acute lymphoblastic leukemia (ALL) is a genetically and prognostically
heterogeneous malignancy with a mortality rate of 20%[1]. The identification of novel …

miRNAs as predictive biomarkers of response to treatment in pediatric patients with acute lymphoblastic leukemia

E Tsotridou, E Georgiou, A Tragiannidis… - Oncology …, 2023 - spandidos-publications.com
MicroRNAs (miRNAs/miRs) are promising prognostic biomarkers in pediatric acute
lymphoblastic leukemia (ALL). The present study aimed to identify miRNAs that could serve …

[HTML][HTML] A microRNA signature for clinical outcomes of pediatric ALL patients treated with TPOG protocols

YH Chang, ST Jou, CT Yen, CY Lin, CH Yu… - American Journal of …, 2022 - ncbi.nlm.nih.gov
MicroRNA (miRNA) expression is reportedly associated with clinical outcomes in childhood
acute lymphoblastic leukemia (ALL). Here, we aimed at investigating whether miRNA …

MicroRNA as a prognostic biomarker for survival in childhood acute lymphoblastic leukemia: a systematic review

WM Rashed, MM Hamza, M Matboli… - Cancer and Metastasis …, 2019 - Springer
Recent studies suggest abnormal microRNA (miRNA) expression may have potential
prognostic value in childhood acute lymphoblastic leukemia (ALL). In this systematic review …

Prospective evaluation of whole genome microRNA expression profiling in childhood acute lymphoblastic leukemia

M Duyu, B Durmaz, C Gunduz, C Vergin… - BioMed research …, 2014 - Wiley Online Library
Dysregulation of microRNA (miRNA) expression contributes to the pathogenesis of several
clinical conditions. The aim of this study is to evaluate the associations between miRNAs …

MicroRNA as a diagnostic biomarker in childhood acute lymphoblastic leukemia; systematic review, meta-analysis and recommendations

WM Rashed, AM Hammad, AM Saad… - Critical reviews in …, 2019 - Elsevier
Several studies detected abnormal mi-RNAs expression levels in childhood Acute
Lymphoblastic Leukemia (ALL) with potential diagnostic value. We conducted a systematic …

MicroRNAs and the diagnosis of childhood acute lymphoblastic leukemia: systematic review, meta-analysis and re-analysis with novel small RNA-seq tools

I Kyriakidis, K Kyriakidis, A Tsezou - Cancers, 2022 - mdpi.com
Simple Summary MicroRNAs (miRNAs) have been under the spotlight for the last three
decades. These non-coding RNAs seem to be dynamic regulators of mRNA stability and …

miRNA deregulation in childhood acute lymphoblastic leukemia: A systematic review

A Gutierrez-Camino, S Garcia-Obregon… - …, 2020 - Taylor & Francis
Despite remarkable improvements in survival of childhood acute lymphoblastic leukemia
(ALL), nonresponding or relapsing patients still represent one of the most frequent causes of …

[HTML][HTML] MicroRNA signatures in blood or bone marrow distinguish subtypes of pediatric acute lymphoblastic leukemia

RA Nair, VK Verma, SS Beevi, A Rawoof… - Translational …, 2020 - Elsevier
OncomiRs are microRNAs that are associated with early onset of specific cancers. To
identify microRNAs involved in pediatric acute lymphoblastic leukemia (ALL) subtypes T …

MicroRNA expression and activity in pediatric acute lymphoblastic leukemia (ALL)

JC de Oliveira, MS Brassesco… - Pediatric Blood & …, 2012 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is the most common type of pediatric neoplasia. Highly
heterogeneous, ALL includes several genetic subtypes with varying clinical outcome …