From the bench to the bedside in the big data age: ethics and practices of consent and privacy for clinical genomics and personalized medicine

PA Chow-White, M MacAulay, A Charters… - Ethics and Information …, 2015 - Springer
Scientists and clinicians are starting to translate genomic discoveries from research labs to
the clinical setting. In the process, big data genomic technologies are both a risk to …

Genomics and the public health code of ethics

JC Thomas, DE Irwin, ES Zuiker… - American Journal of …, 2005 - ajph.aphapublications.org
We consider the public health applications of genomic technologies as viewed through the
lens of the public health code of ethics. We note, for example, the potential for genomics to …

Health system implications of direct-to-consumer personal genome testing

AL McGuire, W Burke - Public Health Genomics, 2010 - karger.com
Direct-to-consumer personal genome testing is now widely available to consumers.
Proponents argue that knowledge is power but critics worry about consumer safety and …

[图书][B] Populations and genetics: legal and socio-ethical perspectives

BM Knoppers - 2003 - books.google.com
Genetic research and testing is not limited to individuals and their families. Increasingly,
there is focus on communities and even whole populations. This raises legal and socio …

The past, present, and future of informed consent in research and translational medicine

SM Wolf, EW Clayton… - The Journal of Law …, 2018 - journals.sagepub.com
Susan M. Wolf, JD, is McKnight Presidential Professor of Law, Medicine & Public Policy;
Faegre Baker Daniels Professor of Law; Professor of Medicine; and Chair of the Consortium …

Broadening research consent in the era of genome-informed medicine

C Kronenthal, SK Delaney, MF Christman - Genetics in Medicine, 2012 - nature.com
Genetic variant associations and advances in research technologies are generating an
unprecedented volume of genomic data. Whole-genome sequencing will introduce even …

Consent and population genomics: the creation of generic tools

S Wallace, S Lazor, BM Knoppers - IRB: Ethics & Human Research, 2009 - JSTOR
In recent years, the number of genomic databases or" biobanks" being created for use in
research has grown significantly. While the term" biobank" has been used to describe many …

Beyond consent: ethical and social issues in genetic testing

MM Burgess - Nature Reviews Genetics, 2001 - nature.com
Informed consent is a vital ethical doctrine in clinical medicine and, through genetic
counselling, is being applied to genetic testing. But genetic testing raises issues that …

Genetics and public health in the 21st century: using genetic information to improve health and prevent disease

MJ Khoury, W Burke, EJ Thomson - 2000 - books.google.com
With the accelerating discovery of human genes, public health professionals are
increasingly confronted with a large body of scientific information that will guide public …

The Human Genome Organisation: towards next-generation ethics

BM Knoppers, A Thorogood, R Chadwick - Genome medicine, 2013 - Springer
© 2013 BioMed Central Ltd accompanying the emergence of population genomic
sequencing technologies. This is especially true in light of genomic science's rapid …