Advances and declining costs in sequencing technology will result in increasing number of
studies with individual sequence data linked to phenotypic information, which has been …

Recent advances in sequencing technology are making possible the application of large-
scale genomic analyses to individualized care, both in wellness and disease. However, a …

As genetic sequencing capabilities become more powerful and costs decline, the reach of
genomics is expanding beyond research laboratories to the wards, outpatient clinics, and …

An ethical quandary is emerging over custodianship of and access to DNA specimens and
attached data, clinical and genetic, held in large disease cohort collections. The balance of …

Purpose Data sharing between clinicians, laboratories, and patients is essential for
improvements in genomic medicine, but obtaining consent for individual-level data sharing …

The transformative potential of whole genome sequencing (WGS) as a diagnostic tool in
healthcare has been demonstrated by initiatives including the 100,000 Genomes Project …

As scientific understandings of genetics advance, researchers require increasingly rich
datasets that combine genomic data from large numbers of individuals with medical and …

The ongoing legal and bioethics debates on consent requirements for collecting, storing,
and utilizing human biological material for purposes of basic and applied research—that is …

Although the explosive growth of direct-to-consumer (DTC) genetic testing has moderated, a
substantial number of patients are choosing to undergo genetic testing outside the purview …

The rapid emergence of large-scale genetic databases raises issues at the nexus of medical
law and ethics, as well as the need, at both national and international levels, for an …