Targeting macrophage immunometabolism: Dawn in the darkness of sepsis
V Kumar - International Immunopharmacology, 2018 - Elsevier
Sepsis is known since the time (470 BC) of great Greek physician, Hippocrates.
Advancement in modern medicine and establishment of separate branches of medical …
Advancement in modern medicine and establishment of separate branches of medical …
Immunometabolism: another road to sepsis and its therapeutic targeting
V Kumar - Inflammation, 2019 - Springer
Sepsis is a major health problem all over the world. Despite its existence since the time of
Hippocrates (470 BC), sepsis is still a serious medical problem for physicians working in …
Hippocrates (470 BC), sepsis is still a serious medical problem for physicians working in …
Treatment advances in sepsis and septic shock: modulating pro-and anti-inflammatory mechanisms
Sepsis is currently defined as a life-threatening organ dysfunction caused by a dysregulated
host response to infection, and it affects over 25 million people every year. Even more …
host response to infection, and it affects over 25 million people every year. Even more …
Current trends in inflammatory and immunomodulatory mediators in sepsis
Review on sepsis mediators, and roles in innate and adaptive immune systems, as well as
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
RS Hotchkiss, G Monneret, D Payen - Nature Reviews Immunology, 2013 - nature.com
Sepsis—which is a severe life-threatening infection with organ dysfunction—initiates a
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …
Therapeutic approaches to innate immunity: severe sepsis and septic shock
Severe sepsis leading to shock is the principal cause of death in non-cardiac intensive care
units. This condition develops because of a dysregulation in host responses, such that the …
units. This condition develops because of a dysregulation in host responses, such that the …
[HTML][HTML] Sepsis: from bench to bedside
E Silva, RDH Passos, MB Ferri, LFP de Figueiredo - Clinics, 2008 - Elsevier
Sepsis is a syndrome related to severe infections. It is defined as the systemic host response
to microorganisms in previously sterile tissues and is characterized by end-organ …
to microorganisms in previously sterile tissues and is characterized by end-organ …
Immunosuppression in sepsis
K Lyn-Kew, TJ Standiford - Current pharmaceutical design, 2008 - ingentaconnect.com
The often fatal sepsis syndrome is characterized by the systemic release of inflammatory
mediators, which is regulated and counterbalanced by the coordinated expression of anti …
mediators, which is regulated and counterbalanced by the coordinated expression of anti …
[HTML][HTML] Sepsis—pathophysiology and therapeutic concepts
D Jarczak, S Kluge, A Nierhaus - Frontiers in medicine, 2021 - frontiersin.org
Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …
[HTML][HTML] Precision immunotherapy for sepsis
Decades of sepsis research into a specific immune system-targeting adjunctive therapy
have not resulted in the discovery of an effective compound. Apart from antibiotics, source …
have not resulted in the discovery of an effective compound. Apart from antibiotics, source …