Defining the impact of family history on detection of high-grade prostate cancer in a large multi-institutional cohort

MB Clements, EA Vertosick, L Guerrios-Rivera… - European urology, 2022 - Elsevier
Background The risk of high-grade prostate cancer, given a family history of cancer, has
been described in the general population, but not among men selected for prostate biopsy in …

Does positive family history of prostate cancer increase the risk of prostate cancer on initial prostate biopsy?

A Elshafei, AS Moussa, A Hatem, V Ethan… - Urology, 2013 - Elsevier
OBJECTIVE: To assess the role of family history (FH) in the risk of a positive prostate biopsy
(PBx) in a large North American biopsy population as earlier reports showed increased risk …

Prostate cancer risk with positive family history, normal prostate examination findings, and PSA less than 4.0 ng/mL

E Canby-Hagino, J Hernandez, TC Brand, DA Troyer… - Urology, 2007 - Elsevier
OBJECTIVES: Family history has been identified as a risk factor for prostate cancer. We
assessed the risk of prostate cancer in men with a positive family history (at least one first …

A positive family history as a risk factor for prostate cancer in a population‐based study with organised prostate‐specific antigen screening: results of the Swiss …

M Randazzo, A Müller, S Carlsson, D Eberli… - BJU …, 2016 - Wiley Online Library
Objective To assess the value of a positive family history (FH) as a risk factor for prostate
cancer incidence and grade among men undergoing organised prostate‐specific antigen …

Prostate cancer incidence and mortality in relationship to family history of prostate cancer; findings from the PLCO trial

O Abdel-Rahman - Clinical genitourinary cancer, 2019 - Elsevier
Background The purpose of the study was to determine the relationship between family
history of prostate cancer in a first-degree relative (FDR) and prostate cancer incidence and …

Incorporation of detailed family history from the Swedish Family Cancer Database into the PCPT risk calculator

S Grill, M Fallah, RJ Leach, IM Thompson… - The Journal of …, 2015 - Elsevier
Purpose A detailed family history provides an inexpensive alternative to genetic profiling for
individual risk assessment. We updated the PCPT Risk Calculator to include detailed family …

Effects of prostate-specific antigen testing on familial prostate cancer risk estimates

O Bratt, H Garmo, J Adolfsson… - Journal of the …, 2010 - academic.oup.com
Background Family history is a strong risk factor for prostate cancer. The aim of this study
was to investigate whether increased diagnostic activity is related to the incidence of …

Family history and probability of prostate cancer, differentiated by risk category: a nationwide population-based study

O Bratt, L Drevin, O Akre, H Garmo… - Journal of the National …, 2016 - academic.oup.com
Background: Familial prostate cancer risk estimates are inflated by clinically insignificant low-
risk cancer, diagnosed after prostate-specific antigen testing. We provide age-specific …

Early onset prostate cancer: predictors of clinical grade

SV Kotsis, SL Spencer, PA Peyser, JE Montie… - The Journal of …, 2002 - auajournals.org
Purpose: Prostate cancer is typically a disease of elderly men and, therefore, it has not been
well characterized in those affected at a young age. With the advent of serum prostate …

The influence of family history on prostate cancer risk: implications for clinical management

S Madersbacher, A Alcaraz, M Emberton… - BJU …, 2011 - Wiley Online Library
What's known on the subject? and What does the study add? A family history of prostate
cancer has long been identified as an important risk factor for developing the disease. This …