A glass full of optimism: enrichment effects on cognitive bias in a rat model of depression

SH Richter, A Schick, C Hoyer, K Lankisch… - Cognitive, Affective, & …, 2012 - Springer
Investigations of cognitive biases in animals are conceptually and translationally valuable
because they contribute to animal welfare research and help to extend and refine our …

[HTML][HTML] Association between a directly translated cognitive measure of negative bias and self-reported psychiatric symptoms

L Daniel-Watanabe, M McLaughlin, S Gormley… - Biological Psychiatry …, 2022 - Elsevier
Background Negative interpretation biases are thought to be core symptoms of mood and
anxiety disorders. However, prior work using cognitive tasks to measure such biases is …

Effect of acute antidepressant administration on negative affective bias in depressed patients

CJ Harmer D Phil, U O'Sullivan… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: Acute administration of an antidepressant increases positive affective processing
in healthy volunteers, an effect that may be relevant to the therapeutic actions of these …

Using an experimental medicine model to explore combination effects of pharmacological and cognitive interventions for depression and anxiety

M Browning, M Grol, V Ly, GM Goodwin… - …, 2011 - nature.com
Selective serotonergic reuptake inhibitors (SSRIs) and cognitive therapies are effective in
the treatment of anxiety and depression. Previous research suggests that both forms of …

Evidence against mood-congruent attentional bias in Major Depressive Disorder

P Cheng, SD Preston, J Jonides, AH Mohr… - Psychiatry …, 2015 - Elsevier
Depression is consistently associated with biased retrieval and interpretation of affective
stimuli, but evidence for depressive bias in earlier cognitive processing, such as attention, is …

The effects of drugs on human models of emotional processing: an account of antidepressant drug treatment

A Pringle, CJ Harmer - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
Human models of emotional processing suggest that the direct effect of successful
antidepressant drug treatment may be to modify biases in the processing of emotional …

Translating a rodent measure of negative bias into humans: the impact of induced anxiety and unmedicated mood and anxiety disorders

J Aylward, C Hales, E Robinson… - Psychological …, 2020 - cambridge.org
BackgroundMood and anxiety disorders are ubiquitous but current treatment options are
ineffective for many sufferers. Moreover, a number of promising pre-clinical interventions …

Efficacy markers in depression

CJ Harmer, PJ Cowen… - Journal of …, 2011 - journals.sagepub.com
Current antidepressant agents are similar in efficacy to the original drugs discovered in the
1950s. The development of new treatments for depression is, however, limited by the …

Emotional biases and recurrence in major depressive disorder. Results of 2.5 years follow-up of drug-free cohort vulnerable for recurrence

HG Ruhe, RJT Mocking, CA Figueroa… - Frontiers in …, 2019 - frontiersin.org
An interesting factor explaining recurrence risk in Major Depressive Disorder (MDD) may be
neuropsychological functioning, ie, processing of emotional stimuli/information. Negatively …

Rodent tests of depression and anxiety: Construct validity and translational relevance

S Gencturk, G Unal - Cognitive, Affective, & Behavioral Neuroscience, 2024 - Springer
Behavioral testing constitutes the primary method to measure the emotional states of
nonhuman animals in preclinical research. Emerging as the characteristic tool of the …