Cell competition is emerging as a quality-control mechanism that eliminates unfit cells in a
wide range of settings from development to the adult. However, the nature of the cells …

The process of embryonic development involves remarkable cellular plasticity, which
governs the coordination between cells necessary to build an organism. One role of this …

Mitochondrial efficiency directs cell fate | Nature Cell Biology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Metabolic characteristics of adult stem cells are distinct from their differentiated progeny, and
cellular metabolism is emerging as a potential driver of cell fate conversions,,–. How these …

Mitochondrial activity differs markedly between organs, but it is not known how and when
this arises. Here we show that cell lineage-specific expression profiles involving essential …

Differentiation of stem/progenitor cells is associated with a substantial increase in
mitochondrial mass and complexity. Mitochondrial dynamics, including the processes of …

Although it is well described that mitochondria are at the epicentre of the energy demands of
a cell, it is becoming important to consider how each cell tailors its mitochondrial …

Although mitochondria are ubiquitous organelles, they exhibit tissue-specific morphology,
dynamics and function. Here, we describe a robust approach to isolate mitochondria from …

Many conserved eukaryotic traits, including apoptosis, two sexes, speciation and ageing,
can be causally linked to a bioenergetic requirement for mitochondrial genes. Mitochondrial …

Mitochondria contain their own genomes that, unlike nuclear genomes, are inherited only in
the maternal line. Owing to a high mutation rate and low levels of recombination of …