Early detection of consciousness in patients with acute severe traumatic brain injury

BL Edlow, C Chatelle, CA Spencer, CJ Chu, YG Bodien… - Brain, 2017 - academic.oup.com
Abstract See Schiff (doi: 10.1093/awx209) for a scientific commentary on this article. Patients
with acute severe traumatic brain injury may recover consciousness before self-expression …

Assessment of covert consciousness in the intensive care unit: clinical and ethical considerations

BL Edlow, JJ Fins - The Journal of head trauma rehabilitation, 2018 - journals.lww.com
Objective: To propose a practical ethical framework for how task-based functional magnetic
resonance imaging (fMRI) and electroencephalography (EEG) may be used in the intensive …

[HTML][HTML] Measuring consciousness in the intensive care unit

BL Edlow, M Fecchio, YG Bodien, A Comanducci… - Neurocritical Care, 2023 - Springer
Early reemergence of consciousness predicts long-term functional recovery for patients with
severe brain injury. However, tools to reliably detect consciousness in the intensive care unit …

Detecting and interpreting conscious experiences in behaviorally non-responsive patients

L Naci, L Sinai, AM Owen - Neuroimage, 2017 - Elsevier
Decoding the contents of consciousness from brain activity is one of the most challenging
frontiers of cognitive neuroscience. The ability to interpret mental content without recourse to …

Injury patterns associated with cognitive motor dissociation

E Franzova, Q Shen, K Doyle, JM Chen, J Egbebike… - Brain, 2023 - academic.oup.com
In unconscious appearing patients with acute brain injury, wilful brain activation to motor
commands without behavioural signs of command following, known as cognitive motor …

Disorders of consciousness after acquired brain injury: the state of the science

JT Giacino, JJ Fins, S Laureys, ND Schiff - Nature Reviews Neurology, 2014 - nature.com
The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

[HTML][HTML] Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Characterization of EEG signals revealing covert cognition in the injured brain

WH Curley, PB Forgacs, HU Voss, MM Conte… - Brain, 2018 - academic.oup.com
Abstract See Boly and Laureys (doi: 10.1093/brain/awy080) for a scientific commentary on
this article. Patients with severe brain injury are difficult to assess and frequently subject to …

How should functional imaging of patients with disorders of consciousness contribute to their clinical rehabilitation needs?

S Laureys, JT Giacino, ND Schiff… - Current opinion in …, 2006 - journals.lww.com
Without controlled studies and careful patient selection criteria it will not be possible to
evaluate the potential of therapeutic interventions in disorders of consciousness. There also …

Update on neuroimaging in disorders of consciousness

LRD Sanz, A Thibaut, BL Edlow… - Current opinion in …, 2021 - journals.lww.com
Each neuroimaging technique conveys advantages and pitfalls to assess consciousness.
We recommend a multimodal approach in which complementary techniques provide …