MicroRNAs are potential therapeutic targets for metabolic diseases. Here, miR-1224-5p was
highly expressed in the livers of mice fed a high-fat diet (HFD) and in obese (ob/ob) mice. To …

In a microarray study, we found that hepatic miR-291b-3p was significantly increased in
leptin-receptor-deficient type 2 mice (db/db), a mouse model of diabetes. The function of miR …

AIM: To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …

Emerging studies have demonstrated that microRNAs (miRs) are profoundly involved in non-
alcoholic fatty liver disease (NAFLD) and related metabolic diseases. Previously, we …

MicroRNAs, a class of small noncoding RNAs, are implicated in controlling a variety of
biological processes. We have shown that leucine deprivation suppresses lipogenesis by …

MicroRNAs (miRNAs) are endogenous, noncoding, short, single-stranded RNAs that are
evolutionarily conserved and believed to play a role in controlling a variety of biological …

Current understanding of microRNA (miRNA) biology is limited, and antisense
oligonucleotide (ASO) inhibition of miRNAs is a powerful technique for their …

Obesity is associated with an increased risk of developing insulin resistance (IR) and type 2
diabetes (T2D). A diverse group of factors including miRNA has been implicated in the …

Background Diet-induced obesity can result in the development of a diverse spectrum of
cardiovascular and metabolic diseases, including type 2 diabetes, dyslipidemia, non …

MicroRNAs (miRNAs) are part of a complex regulatory network that modulates cellular lipid
metabolism. Here, we identify miR-124 as a regulator of triglyceride (TG) metabolism. This …