Synthetic Development of Cyanine Dyes and Investigation of Their Interaction with Duplex DNA

C Holder - 2016 - scholarworks.gsu.edu
This thesis outlines two projects that examine interactions between DNA and cyanine dyes:
1) Investigation of monomethine cyanine dye through the synthesis and optical …

Analysis Of DNA Interactions and Photocleavage by Phenyl Meso Substituted Cyanine Dyes In The Near-Infrared Range

C Fischer - 2017 - scholarworks.gsu.edu
Cyanine dyes are attractive photosensitizers for photodynamic therapy due to their ease of
structure modification and intense absorption in the near-infrared range. Photosensitizers …

Synthesis of Cyanine Dyes and Their Use as Duplex DNA PhotoCleavage Agents

H Argueta-Gonzalez - 2017 - scholarworks.gsu.edu
Cyanine dyes consist of two terminal heterocyclic rings with nitrogen centers with one
bearing a positive charge and are connected via an odd number polymethine chain. With …

Investigation and Characterization of Novel Pentamethine Cyanine Dyes for Use as Photosensitizers in Photodynamic Therapy

K Kiernan - 2017 - scholarworks.gsu.edu
Cyanine dyes that absorb light in the near infrared to far red region of the electromagnetic
spectrum are desirable as photosensitizers for photodynamic cancer therapy. Light of …

DNA Photo-cleavage and Interactions by Quinoline Cyanine Dyes; Towards Improving Photodynamic Cancer Therapy

T Fatemipouya - 2016 - scholarworks.gsu.edu
Photodynamic therapy (PDT) is a cancer treatment method in which a photosensitizer, light
of a particular wavelength, and also oxygen are used to destroy cancerous cells. Cancer …

Synthesis and study of nucleic acids interactions of novel monomethine cyanine dyes

S Kaloyanova, I Crnolatac, N Lesev, I Piantanida… - Dyes and pigments, 2012 - Elsevier
Six asymmetric monomethine cyanine dyes have been synthesized and their spectral
characteristics and interaction with double stranded (ds) DNA have been investigated for …

Synthesis, Characterization, Optical Properties and DNA Cleavage Study of Symmetrical Pentamethine Cyanine Dyes Containing Quinoline Moieties

K Ilina - 2020 - scholarworks.gsu.edu
This thesis outlines a review of the history, synthetic procedures, optical properties, and
applications of quinoline-containing cyanine dyes in the first chapter. The second chapter …

Investigation of Low-Temperature Effects on DNA Photocleavage Using a Novel Thioether Substituted Cyanine Dye

A Clay - 2018 - scholarworks.gsu.edu
The implications of temperature effects on photochemical processes when it comes to near-
infrared DNA photosensitizing agents are discussed in addition to the unique spectroscopic …

[引用][C] Unprecedented DNA photocleavage above 830 nm by a brominated quinolinium pentamethine carbocyanine dye

K Basnet, K Ilina, K Grant, M Henary… - American Chemical …, 2020 - ACS Publications
Long-wavelength carbocyanine dyes have been widely investigated as sensitizing agents in
photodynamic cancer therapy due to the ability of many of these compounds to absorb light …

DNA photocleavage in the near-infrared wavelength range by 2-quinolinium dicarbocyanine dyes

EO Ahoulou, KK Drinkard, K Basnet, A St. Lorenz… - Molecules, 2020 - mdpi.com
Here, we report the syntheses of two pentamethine cyanine dyes containing quinolinium
rings and substituted with either hydrogen (3) or bromine (4) at the meso carbon. The …