CD40‐CD40 ligand

C van Kooten, J Banchereau - Journal of leukocyte biology, 2000 - Wiley Online Library
CD40 is a cell surface receptor that belongs to the tumor necrosis factor‐R (TNF‐R) family,
and that was first identified and functionally characterized on B lymphocytes. Its critical role …

Functions of CD40 on B cells, dendritic cells and other cells

C van Kooten, J Banchereau - Current opinion in immunology, 1997 - Elsevier
CD40 is a cell surface receptor that belongs to the tumor necrosis factor receptor family. It
was first identified and functionally characterized on B lymphocytes; however, in recent …

Functional role of CD40 and its ligand

C van Kooten, J Banchereau - International archives of allergy and …, 1997 - karger.com
CD40, a cell surface receptor which belongs to the TNF-R family, was first identified and
functionally characterized on B lymphocytes. In recent years, CD40 has been found …

The Cd40 ligand: The center of the immune universe?

IS Grewal, RA Flavell - Immunologic research, 1997 - Springer
For several years, the primary function of CD40 ligand (CD40L) has been believed to be in
regulation of contact-dependent, CD40-CD40L-mediated signals between B-and T-cells …

CD40-CD40 ligand: a multifunctional receptor-ligand pair

C Van Kooten, J Banchereau - Advances in immunology, 1996 - Elsevier
A decade has passed since monoclonal antibodies allowed the identification of the CD40
antigen. Meanwhile it has become clear that, in addition to soluble factors (cytokines), direct …

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

MR Alderson, RJ Armitage, TW Tough… - The Journal of …, 1993 - rupress.org
CD40 is a member of the tumor necrosis factor (TNF) receptor family of cell surface proteins
and was originally described as a B cell restricted antigen. Treatment of primary human …

The role of CD40-CD154 interactions in the regulation of cell mediated immunity

A Miga, S Masters, M Gonzalez… - Immunological …, 2000 - Taylor & Francis
CD40 is expressed on a diverse array of cell types from the hematopoeitic and non-
hematopoeitic compartments. Within the hematopoeitic compartment, CD40 is found …

CD40 and its crucial role as a member of the TNFR family

LA Vogel, RJ Noelle - Seminars in immunology, 1998 - Elsevier
The cell surface molecule CD40 is a member of the tumor necrosis factor receptor (TNFR)
family and plays a pivotal role in the immune system due in part to its wide tissue …

Structural characteristics of CD40 ligand that determine biological function

WC Fanslow, S Srinivasan, R Paxton, MG Gibson… - Seminars in …, 1994 - Elsevier
Abstract CD40 ligand (CD40L) is a 33 kDa type II glycoprotein which is transiently
expressed on the surface of T cells following activation. The demonstration that signals …

Recombinant Soluble Trimeric CD40 Ligand Is Biologically Active∗

A Durandy, JF Gauchat, GJ Mazzei… - Journal of Biological …, 1995 - ASBMB
CD40 ligand (CD40L) is expressed on the surface of activated CD4+ T cells, basophils, and
mast cells. Binding of C40L to its receptor, CD40, on the surface of B cells stimulates B cell …