Signaling through the cell surface molecule, CD40, is known to play an important role in the
proliferation and differentiation of B lymphocytes. Using the thymoma cell line EL4, we …

The purpose of this study was to determine whether human fibroblasts express CD40, a 50-
kDa member of the tumor necrosis factor-a-receptor superfamily. CD40 is an important …

A successful immune response requires the coordinated interaction of multiple cell types.
The interactioti between T-helper cells (Th) and antigen-presenting cells (APC) such as B …

The interaction of CD40 ligand (CD40L) on activated T cells with CD40 on B cells,
monocytes and dendritic cells is essential for humoral immunity and for up‐regulation of …

In addition to B cells, CD40 is expressed by a variety of cells including dendritic cells,
monocytes, fibroblasts and vascular endothelial cells. As discussed here by Robert Stout …

CD40 ligand (CD40L) is a glycoprotein expressed on the surface of activated helper T cells,
basophils, mast cells, and eosinophils. Binding of CD40L to its receptor CD40 on the B cell …

CD40, a transmembrane receptor of the tumor necrosis factor gene superfamily is expressed
on a variety of cells, such as monocytes, B‐cells, antigen presenting cells, endothelial …

▪ Abstract Over the past three years, CD40 and its ligand (gp39, CD40L, TBAM) have been
shown to be essential for humoral immune responses to thymus-dependent antigens …

Abstract CD40 and CD40 ligand (CD40L) have been implicated as important molecules for
the transformation of nonactivated antigen-presenting cells (APC) into cells that are potent …

Abstract CD40 and CD40 ligand (CD40L) form one of most important receptor‐ligand pairs
that dock during T‐B cell interactions as part of T‐dependent antibody responses. It has …