Upregulation of ASPM, BUB1B and SPDL1 in tumor tissues predicts poor survival in patients with pancreatic ductal adenocarcinoma

X Tian, N Wang - Oncology Letters, 2020 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) remains a major cause of cancer‑associated
mortality, with poor patient outcome. The present study aimed to identify key candidate …

A comprehensive meta-analysis of transcriptome data to identify signature genes associated with pancreatic ductal adenocarcinoma

SO Kordshouli, A Tahmasebi, A Moghadam… - Plos one, 2024 - journals.plos.org
Purpose Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of less than
5%. Absence of symptoms at primary tumor stages, as well as high aggressiveness of the …

[HTML][HTML] Identification of potential target genes in pancreatic ductal adenocarcinoma by bioinformatics analysis

Y Tang, Z Zhang, Y Tang, X Chen… - Oncology …, 2018 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most complicated and fatally
pathogenic human malignancies. Therefore, there is an urgent need to improve our …

Bioinformatic analysis suggests that three hub genes may be a vital prognostic biomarker in pancreatic ductal adenocarcinoma

X Chang, MF Yang, W Fan, LS Wang, J Yao… - Journal of …, 2020 - liebertpub.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies worldwide
due to its ineffective diagnosis and poor prognosis. It is essential to identify differentially …

[HTML][HTML] Identification of hub genes and regulators associated with pancreatic ductal adenocarcinoma based on integrated gene expression profile analysis

M Shang, L Zhang, X Chen, S Zheng - Discovery Medicine, 2019 - discoverymedicine.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies without
effective screening strategy during the early stage. Therefore, a novel screening panel was …

Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics analysis

J Ding, Y Liu, Y Lai - PeerJ, 2020 - peerj.com
Background Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant neoplasm. It is
necessary to improve the understanding of the underlying molecular mechanisms and …

Weighted gene co-expression network analysis reveals key genes involved in pancreatic ductal adenocarcinoma development

M Giulietti, G Occhipinti, G Principato, F Piva - Cellular Oncology, 2016 - Springer
Purpose Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Up
till now, the patient's prognosis remains poor which, among others, is due to the paucity of …

[HTML][HTML] Ten hub genes associated with progression and prognosis of pancreatic carcinoma identified by co-expression analysis

Z Zhou, Y Cheng, Y Jiang, S Liu, M Zhang… - … journal of biological …, 2018 - ncbi.nlm.nih.gov
Since the five-year survival rate is less than 5%, pancreatic ductal adenocarcinoma (PDAC)
remains the 4th cause of cancer-related death. Although PDAC has been repeatedly …

Identification of key regulators of pancreatic ductal adenocarcinoma using bioinformatics analysis of microarray data

N Li, X Zhao, S You - Medicine, 2019 - journals.lww.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of cancer, and its
etiology remains largely unknown. This study aimed to screen a panel of key genes and to …

Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis

Y He, Y Liu, J Gong, C Liu, H Zhang… - Oncology …, 2019 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with a high degree of
malignancy that is difficult to diagnose and treat. The present study integrated PDAC cohort …