Refining the role of 5-HT in postnatal development of brain circuits
Changing serotonin (5-hydroxytryptamine, 5-HT) brain levels during critical periods in
development has long-lasting effects on brain function, particularly on later …
development has long-lasting effects on brain function, particularly on later …
The serotonin 5-HT3 receptor: a novel neurodevelopmental target
Serotonin (5-hydroxytryptamine, 5-HT), next to being an important neurotransmitter, recently
gained attention as a key-regulator of pre-and postnatal development in the mammalian …
gained attention as a key-regulator of pre-and postnatal development in the mammalian …
Serotonin homeostasis and serotonin receptors as actors of cortical construction: special attention to the 5-HT3A and 5-HT6 receptor subtypes
T Vitalis, MS Ansorge, AG Dayer - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Cortical circuits control higher-order cognitive processes and their function is highly
dependent on their structure that emerges during development. The construction of cortical …
dependent on their structure that emerges during development. The construction of cortical …
Dorsal raphe serotonin neurons in mice: immature hyperexcitability transitions to adult state during first three postnatal weeks suggesting sensitive period for …
BD Rood, LH Calizo, D Piel, ZP Spangler… - Journal of …, 2014 - Soc Neuroscience
Trauma during early life is a major risk factor for the development of anxiety disorders and
suggests that the developing brain may be particularly sensitive to perturbation. Increased …
suggests that the developing brain may be particularly sensitive to perturbation. Increased …
Serotonin neuron development: shaping molecular and structural identities
The continuing fascination with serotonin (5‐hydroxytryptamine, 5‐HT) as a nervous system
chemical messenger began with its discovery in the brains of mammals in 1953. Among the …
chemical messenger began with its discovery in the brains of mammals in 1953. Among the …
Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development
Serotonin and its receptors (HTRs) play critical roles in brain development and in the
regulation of cognition, mood, and anxiety. HTRs are highly expressed in human prefrontal …
regulation of cognition, mood, and anxiety. HTRs are highly expressed in human prefrontal …
New lessons from knockout mice: the role of serotonin during development and its possible contribution to the origins of neuropsychiatric disorders
JA Gingrich, MS Ansorge, R Merker, N Weisstaub… - CNS …, 2003 - cambridge.org
Serotonin (5-HT) modulates numerous processes in the central nervous system that are
relevant to neuropsychiatric function and dysfunction. It exerts significant effects on anxiety …
relevant to neuropsychiatric function and dysfunction. It exerts significant effects on anxiety …
Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development
Serotonin (5-HT) is implicated in several aspects of brain development, yet the ontogenetic
expression patterns of 5-HT receptors responsible for transducing specific effects have …
expression patterns of 5-HT receptors responsible for transducing specific effects have …
Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology
Background: Despite more than 60 years of research in the role of serotonin (5-HT) in
psychopathology, many questions still remain. From a developmental perspective, studies …
psychopathology, many questions still remain. From a developmental perspective, studies …
Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-HT) 1A, 5-HT2A, and 5-HT7 …
JC Béïque, B Campbell, P Perring… - Journal of …, 2004 - Soc Neuroscience
The developing prefrontal cortex receives a dense serotonergic innervation, yet little is
known about the actions of serotonin [5-Hydroxytryptamine (5-HT)] in this region during …
known about the actions of serotonin [5-Hydroxytryptamine (5-HT)] in this region during …