Development and initial results of a low cost, disposable, point-of-care testing device for pathogen detection

JP Bearinger, LC Dugan, BR Baker… - IEEE transactions on …, 2010 - ieeexplore.ieee.org
Development of small footprint, disposable, fast, and inexpensive devices for pathogen
detection in the field and clinic would benefit human and veterinary medicine by allowing …

UbiNAAT: a multiplexed point-of-care nucleic acid diagnostic platform for rapid at-home pathogen detection

KP Jiang, S Bennett, EK Heiniger, S Kumar, P Yager - Lab on a Chip, 2024 - pubs.rsc.org
The COVID-19 pandemic increased demands for respiratory disease testing to facilitate
treatment and limit transmission, demonstrating in the process that most existing test options …

Integrated, automated, fast PCR system for point-of-care molecular diagnosis of bacterial infection

D Lee, D Kim, J Han, J Yun, KH Lee, GM Kim, O Kwon… - Sensors, 2021 - mdpi.com
We developed an integrated PCR system that performs automated sample preparation and
fast polymerase chain reaction (PCR) for application in point-of care (POC) testing. This …

Mobile platform for multiplexed detection and differentiation of disease-specific nucleic acid sequences, using microfluidic loop-mediated isothermal amplification and …

W Chen, H Yu, F Sun, A Ornob, R Brisbin… - Analytical …, 2017 - ACS Publications
New tools are needed to enable rapid detection, identification, and reporting of infectious
viral and microbial pathogens in a wide variety of point-of-care applications that impact …

Developments in integrating nucleic acid isothermal amplification and detection systems for point-of-care diagnostics

EA Pumford, J Lu, I Spaczai, ME Prasetyo… - Biosensors and …, 2020 - Elsevier
Early disease detection through point-of-care (POC) testing is vital for quickly treating
patients and preventing the spread of harmful pathogens. Disease diagnosis is generally …

A handheld point-of-care genomic diagnostic system

FB Myers, RH Henrikson, J Bone, LP Lee - PloS one, 2013 - journals.plos.org
The rapid detection and identification of infectious disease pathogens is a critical need for
healthcare in both developed and developing countries. As we gain more insight into the …

“Paper machine” for molecular diagnostics

JT Connelly, JP Rolland, GM Whitesides - Analytical chemistry, 2015 - ACS Publications
Clinical tests based on primer-initiated amplification of specific nucleic acid sequences
achieve high levels of sensitivity and specificity. Despite these desirable characteristics …

MINI: A high-throughput point-of-care device for performing hundreds of nucleic acid tests per day

D McCloskey, J Boza, CE Mason, D Erickson - Biosensors and …, 2022 - Elsevier
There are a variety of infectious diseases with a high incidence and mortality in limited
resource settings that could benefit from rapid point of care molecular diagnosis. Global …

A low‐cost, portable, and practical LAMP device for point‐of‐diagnosis in the field

S Vural Kaymaz, AF Ergenç, AÖ Aytekin… - Biotechnology and …, 2022 - Wiley Online Library
Transition of rapid, ready‐to‐use, and low‐cost nucleic acid‐based detection technologies
from laboratories to points of sample collection has drastically accelerated. However, most of …

Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Y Wang, C Wang, Z Zhou, J Si, S Li, Y Zeng, Y Deng… - Biosensors, 2023 - mdpi.com
Pathogenic pathogens invade the human body through various pathways, causing damage
to host cells, tissues, and their functions, ultimately leading to the development of diseases …