[HTML][HTML] The benefits of heparin use in COVID-19: pleiotropic antiviral activity beyond anticoagulant and anti-inflammatory properties

G Lippi, BM Henry, EJ Favaloro - Seminars in Thrombosis and …, 2023 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), a life-threatening infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing the worst …

[HTML][HTML] The potential role of heparin in patients with COVID-19: beyond the anticoagulant effect. A review

L Gozzo, P Viale, L Longo, DC Vitale… - Frontiers in …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is responsible of
variable clinical manifestations, ranging from no symptoms to severe pneumonia with acute …

[HTML][HTML] Heparin–an old drug with multiple potential targets in Covid‐19 therapy

U Lindahl, JP Li - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
2. Dianne K, Jennings I, Kitchen S, Walker I. Letter in response to article “Systematic review
of viscoelastic testing (TEG/Rotem) in obstetrics and recommendations from the women's …

[HTML][HTML] Inhaled and systemic heparin as a repurposed direct antiviral drug for prevention and treatment of COVID-19

C Conzelmann, JA Müller, L Perkhofer, KMJ Sparrer… - Clinical Medicine, 2020 - Elsevier
Here, we advocate a highly favourable opportunity for the treatment of COVID-19 disease by
repurposing a long-serving medical agent with an excellent history of clinical use, namely …

[HTML][HTML] The role of heparin in COVID-19: an update after two years of pandemics

M Mangiafico, A Caff, L Costanzo - Journal of Clinical Medicine, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of venous
thromboembolism (VTE) and coagulopathy, especially in critically ill patients. Endothelial …

Type and dose of heparin in Covid‐19: Reply

J Thachil, N Tang, S Gando, A Falanga… - Journal of Thrombosis …, 2020 - jthjournal.org
We thank the authors for their comments and feedback on the International Society on
Thrombosis and Haemostasis interim guidance. Hypercoagulability is indeed a significant …

[HTML][HTML] Horizons of heparin therapy in COVID-19 and pandemic-related diseases

MV Kondashevskaya - Journal of Evolutionary Biochemistry and …, 2022 - Springer
The disease caused by the coronavirus SARS-CoV-2, named COVID-19, has been spread
around the world at a high transmission rate. It was initially considered to be an acute …

[HTML][HTML] The versatile heparin in COVID‐19

J Thachil - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
Coagulopathy in coronavirus infection has been shown to be associated with high mortality
with high D-dimers being a particularly important marker for the coagulopathy. 1 In the latest …

Heparin as a therapy for COVID-19: current evidence and future possibilities

JA Hippensteel, WB LaRiviere… - … of Physiology-Lung …, 2020 - journals.physiology.org
Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every …

[HTML][HTML] Heparin–Messias or Verschlimmbesserung?

D Swan, M Carrier, T Lisman, J Thachil - Journal of Thrombosis and …, 2021 - Elsevier
A heightened risk of thrombosis noted early on with the severe acute respiratory syndrome
coronavirus 2 infection led to the widespread use of heparin anticoagulation in the …