Background: Obesity was traditionally considered as a positive regulator on the strength of
bone. With the in-depth study, obesity is considered as a major risk factor for osteoporosis …

Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. Clinical and animal experiments reveal that age-related OA is …

The humoral cross-talk between bone and fat is an area of increasing interest. We
investigated the expression and regulation of the bone-acting cytokines; bone …

Obesity is traditionally viewed to be beneficial to bone health because of well-established
positive effect of mechanical loading conferred by body weight on bone formation, despite …

Obesity and osteoporosis are two common chronic diseases, however, the basis for the
correlation between them remains largely unknown. The pro-inflammation cytokine tumor …

Osteoimmunology is a new subject which focuses on the communication between the
immune and the skeletal systems. Both the immune system and bone communicate with …

Glucocorticoids are widely used to treat varieties of allergic and autoimmune diseases,
however, long-term application results in glucocorticoid-induced osteoporosis (GIOP) …

Obesity and osteoporosis are two alarming health disorders prominent among middle and
old age populations, and the numbers of those affected by these two disorders are …

The complicated connections and cross talk between the skeletal system and the immune
system are attracting more attention, which is developing into the field of Osteoimmunology …

Discoveries in the last few years have emphasized the existence of an enormous breadth of
communication between bone and the immune system in maintaining skeletal homeostasis …