Dynamic O-(2-[18F] fluoroethyl)-L-tyrosine (F-18 FET) PET for glioma grading: assessment of individual probability of malignancy

ML Calcagni, G Galli, A Giordano, S Taralli… - Clinical nuclear …, 2011 - journals.lww.com
Purpose:(1) To investigate the diagnostic value of some O-(2-[18 F] fluoroethyl)-L-tyrosine (F-
18 FET) indices derived from the dynamic acquisition to differentiate low-grade gliomas from …

Feature-based PET/MRI radiomics in patients with brain tumors

P Lohmann, AK Meißner, M Kocher… - Neuro-oncology …, 2020 - academic.oup.com
Radiomics allows the extraction of quantitative features from medical images such as CT,
MRI, or PET, thereby providing additional, potentially relevant diagnostic information for …

Predicting isocitrate dehydrogenase (IDH) mutation status in gliomas using multiparameter MRI radiomics features

H Peng, J Huo, B Li, Y Cui, H Zhang… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Accurate and noninvasive detection of isocitrate dehydrogenase (IDH,
including IDH1 and IDH2) status is clinically meaningful for molecular stratification of glioma …

Machine learning reveals multimodal MRI patterns predictive of isocitrate dehydrogenase and 1p/19q status in diffuse low-and high-grade gliomas

H Zhou, K Chang, HX Bai, B Xiao, C Su, WL Bi… - Journal of neuro …, 2019 - Springer
Purpose Isocitrate dehydrogenase (IDH) and 1p19q codeletion status are importantin
providing prognostic information as well as prediction of treatment response in gliomas …

[HTML][HTML] The value of FET PET/CT in recurrent glioma with a different IDH mutation status: the relationship between imaging and molecular biomarkers

M Skoblar Vidmar, A Doma, U Smrdel, K Zevnik… - International Journal of …, 2022 - mdpi.com
The evaluation of treatment response remains a challenge in glioma cases because the
neuro oncological therapy can lead to the development of treatment-related changes (TRC) …

Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma

NL Albert, DV Nelwan, DF Fleischmann… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The 18-kDa translocator protein (TSPO) is gaining recognition as a relevant target in
glioblastoma imaging. However, data on the potential prognostic value of TSPO PET …

Identification of time-to-peak on dynamic 18F-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma

B Suchorska, A Giese, A Biczok, M Unterrainer… - Neuro …, 2018 - academic.oup.com
Background Stratification of glioma according to isocitrate dehydrogenase 1/2 (IDH1/2)
mutation and 1p/19q codeletion status has gained major importance in the new World …

[HTML][HTML] Lesion location implemented magnetic resonance imaging radiomics for predicting IDH and TERT promoter mutations in grade II/III gliomas

H Arita, M Kinoshita, A Kawaguchi, M Takahashi… - Scientific reports, 2018 - nature.com
Molecular biological characterization of tumors has become a pivotal procedure for glioma
patient care. The aim of this study is to build conventional MRI-based radiomics model to …

[HTML][HTML] Voxel-based 18F-FET PET segmentation and automatic clustering of tumor voxels: A significant association with IDH1 mutation status and survival in patients …

P Blanc-Durand, A Van Der Gucht, A Verger… - PLoS …, 2018 - journals.plos.org
Introduction Aim was to develop a full automatic clustering approach of the time-activity
curves (TAC) from dynamic 18F-FET PET and evaluate its association with IDH1 mutation …

IDH mutation is paradoxically associated with higher 18F-FDOPA PET uptake in diffuse grade II and grade III gliomas

A Verger, P Metellus, Q Sala, C Colin, E Bialecki… - European journal of …, 2017 - Springer
Abstract Purpose The World Health Organization Classification of Tumors of the Central
Nervous System has recently been updated by the integration of diagnostic and prognostic …