Nanoparticles for radiooncology: Mission, vision, challenges

LA Kunz-Schughart, A Dubrovska, C Peitzsch, A Ewe… - Biomaterials, 2017 - Elsevier
Cancer is one of the leading non-communicable diseases with highest mortality rates
worldwide. About half of all cancer patients receive radiation treatment in the course of their …

Synthetic nanoparticles for delivery of radioisotopes and radiosensitizers in cancer therapy

J Zhao, M Zhou, C Li - Cancer nanotechnology, 2016 - Springer
Radiotherapy has been, and will continue to be, a critical modality to treat cancer. Since the
discovery of radiation-induced cytotoxicity in the late 19th century, both external and internal …

Radiosensitization and nanoparticles

T Paunesku, S Gutiontov, K Brown… - … -Based Precision Tools …, 2015 - Springer
Nanomaterials have been shown to have physical and chemical properties that have
opened new avenues for cancer diagnosis and therapy. Nanoconstructs that enhance …

Advances of nanomedicine in radiotherapy

W Liu, B Chen, H Zheng, Y Xing, G Chen, P Zhou… - Pharmaceutics, 2021 - mdpi.com
Radiotherapy (RT) remains one of the current main treatment strategies for many types of
cancer. However, how to improve RT efficiency while reducing its side effects is still a large …

Emerging strategies of nanomaterial‐mediated tumor radiosensitization

J Xie, L Gong, S Zhu, Y Yong, Z Gu… - Advanced …, 2019 - Wiley Online Library
Nano‐radiosensitization has been a hot concept for the past ten years, and the nanomaterial‐
mediated tumor radiosensitization method is mainly focused on increasing intracellular …

[HTML][HTML] Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer

D Kwatra, A Venugopal, S Anant - Translational Cancer Research, 2013 - tcr.amegroups.org
Acquired radiation resistance is one of the major causes of radio therapy failure and
subsequent tumor relapse. Multiple approaches have been utilized to limit the radiation …

[HTML][HTML] Nanoparticle-based radiosensitization strategies for improving radiation therapy

H Shen, H Huang, Z Jiang - Frontiers in Pharmacology, 2023 - frontiersin.org
Radiotherapy remains the mainstay treatment for a variety of cancer forms. However, the
therapeutic efficiency of radiation is significantly limited by several aspects, including high …

Radiolabeled nanomaterial for cancer diagnostics and therapeutics: principles and concepts

M Goel, Y Mackeyev, S Krishnan - Cancer Nanotechnology, 2023 - Springer
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …

Nanotechnology in radiation oncology

AZ Wang, JE Tepper - Journal of Clinical Oncology, 2014 - ascopubs.org
Nanotechnology, the manipulation of matter on atomic and molecular scales, is a relatively
new branch of science. It has already made a significant impact on clinical medicine …

Mechanisms of nanoparticle radiosensitization

I Kempson - Wiley Interdisciplinary Reviews: Nanomedicine …, 2021 - Wiley Online Library
Metal‐based nanoparticles applied to potentiating the effects of radiotherapy have drawn
significant attention from the research community and are now available clinically. By …