Lung Injury Prevention with Aspirin (LIPS-A): a protocol for a multicentre randomised clinical trial in medical patients at high risk of acute lung injury
Introduction Acute lung injury (ALI) is a devastating condition that places a heavy burden on
public health resources. Although the need for effective ALI prevention strategies is …
public health resources. Although the need for effective ALI prevention strategies is …
The effect of aspirin in preventing the acute respiratory distress syndrome/acute lung injury: A meta-analysis
H Yu, YN Ni, ZA Liang, BM Liang, Y Wang - The American Journal of …, 2018 - Elsevier
Background The effects of aspirin in preventing the occurrence of acute respiratory distress
syndrome (ARDS)/acute lung injury (ALI) among adult patients are controversial. We aimed …
syndrome (ARDS)/acute lung injury (ALI) among adult patients are controversial. We aimed …
Prevention or treatment of ARDS with aspirin: a review of preclinical models and meta-analysis of clinical studies
BA Panka, HJ de Grooth, AME Spoelstra-de Man… - Shock, 2017 - journals.lww.com
Background: The acute respiratory distress syndrome (ARDS) is a life-threating disorder that
contributes significantly to critical illness. No specific pharmacological interventions directed …
contributes significantly to critical illness. No specific pharmacological interventions directed …
Association of prehospitalization aspirin therapy and acute lung injury: results of a multicenter international observational study of at-risk patients
DJ Kor, J Erlich, MN Gong, M Malinchoc… - Critical care …, 2011 - journals.lww.com
Objective: To evaluate the association between prehospitalization aspirin therapy and
incident acute lung injury in a heterogeneous cohort of at-risk medical patients. Design: This …
incident acute lung injury in a heterogeneous cohort of at-risk medical patients. Design: This …
Effect of aspirin on development of ARDS in at-risk patients presenting to the emergency department: the LIPS-A randomized clinical trial
Importance Management of acute respiratory distress syndrome (ARDS) remains largely
supportive. Whether early intervention can prevent development of ARDS remains unclear …
supportive. Whether early intervention can prevent development of ARDS remains unclear …
Towards the prevention of acute lung injury: a population based cohort study protocol
SJ Thakur, CA Trillo-Alvarez, MM Malinchoc… - BMC emergency …, 2010 - Springer
Background Acute lung injury (ALI) is an example of a critical care syndrome with limited
treatment options once the condition is fully established. Despite improved understanding of …
treatment options once the condition is fully established. Despite improved understanding of …
Meta-analysis of aspirin use and risk of lung cancer shows notable results
F Hochmuth, M Jochem… - European Journal of …, 2016 - journals.lww.com
Aspirin is a promising agent for chemoprevention of lung cancer. We assessed the
association of aspirin use and the development of lung cancer, with a focus on …
association of aspirin use and the development of lung cancer, with a focus on …
Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk–a multicenter cohort study
Background Few emergency department (ED) evaluations on acute lung injury (ALI) have
been carried out; hence, we sought to describe a cohort of hospitalized ED patients at risk …
been carried out; hence, we sought to describe a cohort of hospitalized ED patients at risk …
Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis
W Chen, DR Janz, JA Bastarache, AK May… - Critical care …, 2015 - journals.lww.com
Objectives: Platelet activation plays an active role in the pathogenesis of acute respiratory
distress syndrome. In our prior study of 575 patients at high risk for acute respiratory distress …
distress syndrome. In our prior study of 575 patients at high risk for acute respiratory distress …
Aspirin in primary prevention: the triumph of clinical judgement over complex equations
F Santilli, P Simeone - Internal and Emergency Medicine, 2019 - Springer
Aspirin, in 2017, has celebrated its 120th birthday. The efficacy and safety of low-dose
aspirin in secondary prevention of cardiovascular disease is well supported by many …
aspirin in secondary prevention of cardiovascular disease is well supported by many …