Psoriasis: from pathogenesis to novel therapeutic approaches

G Monteleone, F Pallone, TT MacDonald… - Clinical …, 2011 - portlandpress.com
Psoriasis is one of the commonest chronic inflammatory disorders. Its cause is unknown, but
a wealth of studies indicate that the disease results from a complex and dynamic interplay …

Psoriasis: emerging therapeutic strategies

AB Gottlieb - Nature reviews Drug discovery, 2005 - nature.com
Psoriasis is a chronic inflammatory skin disorder that is characterized by thickened, scaly
plaques, and is estimated to affect∼ 1–3% of the Caucasian population. Traditional …

Current knowledge on psoriasis and autoimmune diseases

N Ayala-Fontánez, DC Soler… - Psoriasis: Targets and …, 2016 - Taylor & Francis
Psoriasis is a prevalent, chronic inflammatory disease of the skin, mediated by crosstalk
between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen …

Psoriasis: keratinocytes or immune cells–which is the trigger?

F Benhadou, D Mintoff, V Del Marmol - Dermatology, 2019 - karger.com
Background: Psoriasis is a common, chronic inflammatory skin disorder, which can
significantly impact quality of life. Despite major breakthroughs in our understanding of the …

Pathophysiology of psoriasis: science behind therapy

LC Guenther, JP Ortonne - Journal of cutaneous medicine …, 2002 - journals.sagepub.com
Although genetics may predispose patients to psoriasis, environmental triggers may be
necessary for expression of the disease. Hyperproliferation and abnormal differentiation of …

Immunology of psoriasis

C Albanesi - Clinical immunology, 2019 - Elsevier
Psoriasis is a chronic inflammatory autoimmune disease characterized by an excessively
aberrant hyperproliferation of keratinocytes. There is a wide spectrum of cutaneous …

Psoriasis: from pathogenesis to targeted therapies

C Conrad, M Gilliet - Clinical reviews in allergy & immunology, 2018 - Springer
Over the last decade, the management of psoriasis has witnessed a paradigm shift. Thanks
to the increasing knowledge about the pathogenesis of psoriasis, targeted treatments with …

Pathogenesis and immunotherapy in cutaneous psoriasis: what can rheumatologists learn?

H Alexander, FO Nestle - Current opinion in rheumatology, 2017 - journals.lww.com
Pathogenesis and immunotherapy in cutaneous psoriasis: what... : Current Opinion in
Rheumatology Pathogenesis and immunotherapy in cutaneous psoriasis: what can …

Crosstalk: Keratinocytes and immune cells in psoriasis

M Kamata, Y Tada - Frontiers in Immunology, 2023 - frontiersin.org
In the past, psoriasis was considered a skin disease caused only by keratinocyte disorders.
However, the efficacy of immunosuppressive drugs and biologics used to treat psoriasis …

[HTML][HTML] Update on the natural history and systemic treatment of psoriasis

SK Richardson, JM Gelfand - Advances in dermatology, 2008 - ncbi.nlm.nih.gov
Psoriasis is a common inflammatory disease of the skin and joints. Its etiology remains
unknown, however, it has been linked to complex interactions between predisposing genes …