Based on pharmacological criteria, we previously suggested that in the mouse aorta,
endothelium‐dependent relaxation by nucleotides is mediated by P2Y1 (adenosine …

Nucleotides regulate various effects including vascular tone. This study was aimed to
characterize P2Y receptors on endothelial cells of the aorta of C57BL6 mice. Five adjacent …

The contractile and relaxant effects of the different P2 receptors were characterized in the rat
isolated mesenteric artery by use of extracellular nucleotides, including the stable …

The receptors through which 2-methylthio ATP (MeSATP), adenosine 5′-O-(2-
thiodiphosphate)(ADPβS), UTP and ATP elicit endothelium-dependent relaxation of …

P2 receptors mediate the actions of the extracellular nucleotides ATP, ADP, UTP, and UDP,
regulating several physiologic responses including cardiac function, vascular tone, smooth …

Extracellular nucleotides, particularly ATP, are involved in the modulation of arterial
vasomotricity via P2 purinoceptors present on smooth muscle and endothelial cells. These …

Background and purpose: The uracil nucleotides UDP and UTP have been reported to
activate P2Y2, P2Y4 and P2Y6 receptors to cause vasoconstriction. We have performed a …

Previous studies have shown that ATP and UTP are able to stimulate phospholipase C
(PLC) and proliferation in cultured aortic smooth muscle cells. Here we set out to …

ATP is an important vasoactive mediator, which acts via two receptor classes: P2X and P2Y.
Activation of P2X receptors has traditionally been associated with the well‐characterised …

ATP acts at P2 receptors to contract blood vessels and reactivity to vasoconstrictor agents is
often altered in hypertension. This study was designed to identify P2 receptors in mesenteric …