The main aim of this study was to determine the functional effect of 2-methyl-thio-adenosine
diphosphate (2MeS-ADP) on vascular purinoceptors, in comparison with that of a …

1 P2‐purinoceptors were characterized pharmacologically in the constantly perfused
isolated mesenteric arterial vascular bed of the golden hamster. Vasoconstrictor and …

The present study was aimed at examining P2 receptor‐mediated vasodilatation in human
vessels. The isometric tension was recorded in isolated segments of the human left internal …

ATP can be released from endothelial cells, and this release is increased by intraluminal
flow in blood vessels. In the present study, the effect of extracellular ATP (1 μM) on flow …

P2X 1 receptors, the major subtype of P2X receptors in the vascular smooth muscle, are
essential for α, β-methylene adenosine 5′-triphosphate (α, β-MeATP)-induced …

Diadenosine polyphosphates (ApnAs, n= 2–7) are considered as stress mediators in the
cardiovascular system. They act both via identified P2 purinoceptors and via yet to be …

Uridine adenosine tetraphosphate (Up4A) has been identified as an endothelium-derived
contracting factor, which acts through purinergic P2X and P2Y receptors. Since the coronary …

We demonstrated previously that stimulation of the P2Y receptor enhanced the
macromolecular permeability of cultured endothelial cell monolayers via the paracellular …

Unusual absence of endothelium-dependent or-independent vasodilatation to purines or
pyrimidines in the rat renal artery. Background Adenosine triphosphate (ATP) is a …

The actions of ATP and uridine 5′-triphosphate (UTP) were compared at P2X1 receptors in
acutely dissociated smooth muscles cells of the rat tail artery. ATP (30 nM–100 μM) and UTP …