Semaphorins (Semas) are a large family of traditional axon guidance molecules. Through
interactions with their receptors, Plexins and Neuropilins, Semas play critical roles in a …

Semaphorins are a large family of secreted and membrane-bound molecules initially
implicated in the development of the nervous system and in axon guidance. More recently …

Semaphorins are mainly known as guidance signals in development, acting through
receptors called Plexins. However, their role in cancer is rapidly emerging in the regulation …

Semaphorins are a large family of secreted and membrane-bound molecules that were
initially implicated in the development of the nervous system and in axon guidance. More …

The hallmarks of cancer include multiple alterations in the physiological processes occurring
in normal tissues, such as cell proliferation, apoptosis, and restricted cell migration. These …

The semaphorins and their receptors, the neuropilins and the plexins, were originally
characterized as constituents of the complex regulatory system responsible for the guidance …

Semaphorins belong to a large family of proteins well-conserved along evolution from
viruses to mammalians. Secreted and membrane-bound semaphorins participate in a wide …

Angiogenesis, the formation of new blood vessels from preexisting vasculature, is essential
for many physiological processes, and aberrant angiogenesis contributes to some of the …

The semaphorins were initially described as axon guidance factors, but have recently been
implicated in a variety of physiological and developmental functions, including regulation of …

Simple Summary Cancer is the second leading cause of death in the US. In 2023,
approximately 609,820 deaths from cancer are expected. Plexins are a family of receptors …