Obstetricians are increasingly called upon to deal with the pregnant woman's risk for genetic
and cytogenetic conditions. Chromosome disorders are a major category of genetic disease …

The Principles of Clinical Cytogenetics is an essential reference book for all clinical
cytogeneticists. It is written with a unique laboratory focus; it answers the most frequently …

Human Cytogenetics: Clinical Cytogenetics, Volume II presents the general theoretical
principles and clinical aspects of cytogenetics, a branch of genetics that deals specifically …

Chromosome abnormalities account for approximately half of all spontaneous pregnancy
losses, are among the most common etiologies for birth defects, and are the single most …

Antenatal diagnosis of chromosomal abnormalities is a clinically accepted procedure.
Facilities are readily available and increasing numbers of women avail themselves of the …

Genetic disorders traditionally fall into three main categories: single-gene defects,
chromosomal abnormalities, and multifactorial conditions. A chromosomal abnormality, or …

Chromosome analysis is one of the first approaches to genetic testing and remains a key
component of genetic analysis of constitutional and somatic genetic disorders. Numerical or …

First trimester risk screening is probably the major methodological advance in identifying
pregnancies at increased risk for genetic disease during recent years with an impact on all …

The technologies developed for the Human Genome Project, the recent surge of available
DNA sequences resulting from it and the increasing pace of gene discoveries and …

• Chromosomal abnormalities are the basis for a substantial proportion of human morbidity
and mortality. During the past 35 years, the field of human cytogenetics has helped to …