Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19

ATTACC, ACTIV-4a, and REMAP-CAP … - New England Journal …, 2021 - Mass Medical Soc
Background Thrombosis and inflammation may contribute to the risk of death and
complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized …

Therapeutic anticoagulation in critically ill patients with Covid-19–preliminary report

REMAP-CAP, ACTIV-4a, ATTACC Investigators… - MedRxiv, 2021 - medrxiv.org
Background Thrombosis may contribute to morbidity and mortality in Covid-19. We
hypothesized that therapeutic anticoagulation would improve outcomes in critically ill …

Randomized trial of anticoagulation strategies for noncritically ill patients hospitalized with COVID-19

GW Stone, ME Farkouh, A Lala, E Tinuoye… - Journal of the American …, 2023 - jacc.org
Background Prior studies of therapeutic-dose anticoagulation in patients with COVID-19
have reported conflicting results. Objectives We sought to determine the safety and …

Different anticoagulant regimens, mortality, and bleeding in hospitalized patients with COVID-19: a systematic review and an updated meta-analysis

R Parisi, S Costanzo, A Di Castelnuovo… - … in thrombosis and …, 2021 - thieme-connect.com
We conducted a systematic review and a meta-analysis to assess the association of
anticoagulants and their dosage with in-hospital all-cause mortality in COVID-19 patients …

Therapeutic versus prophylactic anticoagulation for severe COVID-19: A randomized phase II clinical trial (HESACOVID)

ACB Lemos, DA do Espírito Santo, MC Salvetti… - Thrombosis research, 2020 - Elsevier
Abstract Introduction Coronavirus disease 2019 (COVID-19) causes a hypercoagulable
state. Several autopsy studies have found microthrombi in pulmonary circulation. Methods In …

Higher anticoagulation targets and risk of thrombotic events in severe COVID-19 patients: bi-center cohort study

J Helms, F Severac, H Merdji, M Schenck… - Annals of intensive …, 2021 - Springer
Background Thromboprophylaxis of COVID-19 patients is a highly debated issue. We aimed
to compare the occurrence of thrombotic/ischemic events in COVID-19 patients with acute …

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week

ME Farkouh, GW Stone, A Lala, E Bagiella… - Journal of the American …, 2022 - jacc.org
Clinical, laboratory, and autopsy findings support an association between coronavirus
disease-2019 (COVID-19) and thromboembolic disease. Acute COVID-19 infection is …

Anticoagulation before hospitalization is a potential protective factor for COVID‐19: insight from a French multicenter cohort study

R Chocron, V Galand, J Cellier, N Gendron… - Journal of the …, 2021 - Am Heart Assoc
Background Coronavirus disease 2019 (COVID‐19) is a respiratory disease associated with
thrombotic outcomes with coagulation and endothelial disorders. Based on that, several …

[HTML][HTML] Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID‐19: a multi‐center, open‐label, randomized controlled trial

US Perepu, I Chambers, A Wahab, P Ten Eyck… - Journal of thrombosis …, 2021 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID‐19) is associated with
coagulopathy but the optimal prophylactic anticoagulation therapy remains uncertain and …

Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19: a systematic review and meta …

L Ortega-Paz, M Galli, D Capodanno… - European Heart …, 2022 - academic.oup.com
Background The clinical impact of different prophylactic anticoagulation regimens among
hospitalized patients with coronavirus disease 2019 (COVID-19) remains unclear. We …