Quantitative magnetic resonance imaging (qMRI) aims to quantify tissue parameters by
eliminating instrumental bias. We describe qMRI theory, simulations, and software designed …

Proton density (PD) refers to the concentration of protons in tissue, protons being the
hydrogen nuclei that resonate and give rise to the NMR signal. Since most visible tissue …

Interest in techniques yielding quantitative information about brain tissue proton densities is
increasing. In general, all parameters influencing the signal amplitude are mapped in …

Most methods for mapping proton densities (PD) in brain tissue are based on measuring all
parameters influencing the signal intensity with subsequent elimination of any weighting not …

Quantitative T1 mapping of brain tissue is frequently based on the variable flip angle (VFA)
method, acquiring spoiled gradient echo (GE) datasets at different excitation angles …

This review on brain multiparametric quantitative MRI (MP-qMRI) focuses on the primary
subset of quantitative MRI (qMRI) parameters that represent the mobile (“free”) and bound …

The use of tissue water as a concentration standard in proton magnetic resonance
spectroscopy (1H‐MRS) of the brain requires that the water proton signal be adjusted for …

Since the brain's gray matter (GM) and white matter (WM) metabolite concentrations differ,
their partial volumes can vary the voxel's 1H MR spectroscopy (1H‐MRS) signal, reducing …

Abstract Background Quantitative MRI (qMRI) techniques allow assessing cerebral tissue
properties. However, previous studies on the accuracy of quantitative T1 and T2 mapping …

Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …