Delineation of the mechanisms that promote the tolerogenic properties of Dendritic cells in
autoimmune diseases Page 1 Delineation of the mechanisms that promote the tolerogenic …

Dendritic cells (DCs) induce and regulate T-cell responses, and tolerogenic DCs can
promote the development of regulatory T cells with suppressive activity. The possibility of …

Autoimmune diseases are characterized by qualitative and quantitative abnormalities in
multiple components of innate and adaptive immunity. Among the cells of the immune …

Dendritic cells (DCs) are highly susceptible to extrinsic signals that modify the functions of
these crucial APCs. Maturation of DCs induced by diverse proinflammatory conditions …

Dendritic cells (DC) have a key role in controlling the immune response, by determining the
outcome of antigen presentation to T cells. Through costimulatory molecules and other …

Autoimmune diseases such as rheumatoid arthritis are severe and common diseases that
together affect~ 3-5% of the population, and for which a new treatment strategy is needed …

Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the
effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in …

In general, immunological tolerance is acquired upon treatment with non‐specific
immunosuppressive drugs. This indiscriminate immunosuppression of the patient often …

Adaptive immune responses are orchestrated by specialized professional antigen-
presenting cells (APCs), the dendritic cells (DCs), which play crucial roles as initiators and …

Dendritic cells (DCs) are uniquely well‐equipped antigen‐presenting cells (APCs) regarded
classically as sentinels of the immune response, which induce and regulate T‐cell reactivity …