This chapter discussed how neuroendocrine findings in posttraumatic stress disorder
(PTSD) potentially inform hypothalamic-pituitary-adrenal (HPA) alterations in PTSD and …

Post-traumatic stress disorder is a severe, debilitating mental disorder with multiple
symptoms that span biological systems and present with medical comorbidities. This …

The findings from investigations of the neuroendocrinology of posttraumatic stress disorder
(PTSD) have highlighted alterations that have not historically been associated with …

At the current time, there are few effective pharmacotherapy options for posttraumatic stress
disorder (PTSD), and no medication strategies targeted towards PTSD prophylaxis. This in …

The majority of studies of post-traumatic stress disorder (PTSD) demonstrate alterations
consistent with an enhanced negative feedback inhibition of cortisol on the pituitary and an …

The acute stress response includes activation of the hypothalamic‐pituitary‐adrenal (HPA)
axis, which leads to the release of cortisol, a glucocorticoid. Through negative feedback …

Neuroendocrine studies examining the hypothalamic-pituitary-adrenal (HPA) axis under
baseline conditions and in response to neuroendocrine challenges have supported the …

The article mentioned above has been retracted by R. Dantzer, Editor-in-Chief, in response
to a request from the Office of Research Integrity, Department of Health and Human …

Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …

Highlights•Low cortisol, enhanced GR function and a pro-inflammatory state have been
repeatedly observed in subpopulations of PTSD patients.•Biological dysregulation may …