How to standardize the multiplicity of methods to evaluate natural antioxidants

EN Frankel, JW Finley - Journal of Agricultural and Food …, 2008 - ACS Publications
A great multiplicity of methods has been used to evaluate the activity of natural antioxidants
by using different techniques of inducing and catalyzing oxidation and measuring the end …

Dietary polyphenols: good, bad, or indifferent for your health?

B Halliwell - Cardiovascular research, 2007 - academic.oup.com
Flavonoids and other polyphenolic compounds have powerful antioxidant effects in vitro in
many test systems, but can act as pro-oxidants in some others. Whether pro-oxidant …

Antioxidants in foods and health: problems and fallacies in the field.

EN Frankel, JB German - 2006 - cabidigitallibrary.org
The need to improve protocol methods to better evaluate the in vivo effects of polyphenolic
compounds in biological systems is discussed, including the revision of human intervention …

[HTML][HTML] The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established1–4

PCH Hollman, A Cassidy, B Comte, M Heinonen… - The Journal of …, 2011 - Elsevier
Human studies provide evidence for beneficial effects of polyphenol-rich foods on
cardiovascular health. The antioxidant activity of polyphenols potentially explains these …

Polyphenols and human health: a prospectus

F Visioli, CADL Lastra, C Andres-Lacueva… - Critical reviews in …, 2011 - Taylor & Francis
The lay press often heralds polyphenols as panacea for all sorts of diseases. The rationale
is that their antioxidant activity would prevent free radical damage to macromolecules …

[HTML][HTML] Polyphenols: antioxidants and beyond

A Scalbert, IT Johnson, M Saltmarsh - The American journal of clinical …, 2005 - Elsevier
Research on the effects of dietary polyphenols on human health has developed
considerably in the past 10 y. It strongly supports a role for polyphenols in the prevention of …

Unravelling of the health effects of polyphenols is a complex puzzle complicated by metabolism

PCH Hollman - Archives of biochemistry and biophysics, 2014 - Elsevier
Plant metabolism creates complex mixtures of polyphenols in plant foods. Epidemiology and
human trials reduced this complexity, by studying specific foods; subclasses of polyphenols; …

Chemistry and biological effects of dietary phenolic compounds: relevance to cardiovascular disease

LW Morton, RAA Caccetta, IB Puddey… - Clinical and …, 2000 - Wiley Online Library
There has been considerable recent interest in the possibility that increased intake of dietary
anti‐oxidants may protect against cardiovascular disease. This is partly due to the …

Plant polyphenols: how to translate their in vitro antioxidant actions to in vivo conditions

CG Fraga - IUBMB life, 2007 - Wiley Online Library
Epidemiological evidence demonstrates that diets rich in fruit and vegetables promote
health, and attenuate, or delay, the onset of various diseases, including cardiovascular …

[HTML][HTML] Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?

B Halliwell, J Rafter, A Jenner - The American journal of clinical nutrition, 2005 - Elsevier
Foods and beverages rich in phenolic compounds, especially flavonoids, have often been
associated with decreased risk of developing several diseases. However, it remains unclear …