Fluctuation of multiple metabolic pathways is required for Escherichia coli in response to chlortetracycline stress

X Lin, L Kang, H Li, X Peng - Molecular BioSystems, 2014 - pubs.rsc.org
Bacterial antibiotic resistance has become a worldwide challenge with the overuse and
misuse of drugs. Several mechanisms for the resistance are revealed, but information …

Bacteria under antibiotic attack: Different strategies for evolutionary adaptation

EM Windels, B Van den Bergh, J Michiels - PLoS pathogens, 2020 - journals.plos.org
Bacteria are well known for their extremely high adaptability in stressful environments. The
clinical relevance of this property is clearly illustrated by the ever-decreasing efficacy of …

Spaceflight Modifies Escherichia coli Gene Expression in Response to Antibiotic Exposure and Reveals Role of Oxidative Stress Response

TR Aunins, KE Erickson, N Prasad, SE Levy… - Frontiers in …, 2018 - frontiersin.org
Bacteria grown in space experiments under microgravity conditions have been found to
undergo unique physiological responses, ranging from modified cell morphology and …

Antibiotic-induced genetic variation: how it arises and how it can be prevented

J Blázquez, J Rodríguez-Beltrán… - Annual review of …, 2018 - annualreviews.org
By targeting essential cellular processes, antibiotics provoke metabolic perturbations and
induce stress responses and genetic variation in bacteria. Here we review current …

Acidification of Cytoplasm in Escherichia coli Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic Resistance

EZ Reyes-Fernández, S Schuldiner - Scientific reports, 2020 - nature.com
Awareness of the problem of antimicrobial resistance (AMR) has escalated, and drug-
resistant infections are named among the most urgent issues facing clinicians today …

Temporal order and precision of complex stress responses in individual bacteria

K Mitosch, G Rieckh, T Bollenbach - Molecular systems biology, 2019 - embopress.org
Sudden stress often triggers diverse, temporally structured gene expression responses in
microbes, but it is largely unknown how variable in time such responses are and if genes …

Comparative Review of the Responses of Listeria monocytogenes and Escherichia coli to Low pH Stress

T Arcari, ML Feger, DN Guerreiro, J Wu, CP O'Byrne - Genes, 2020 - mdpi.com
Acidity is one of the principal physicochemical factors that influence the behavior of
microorganisms in any environment, and their response to it often determines their ability to …

Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments

R Chait, AC Palmer, I Yelin, R Kishony - Nature communications, 2016 - nature.com
Antibiotic-sensitive and-resistant bacteria coexist in natural environments with low, if
detectable, antibiotic concentrations. Except possibly around localized antibiotic sources …

Antibiotics disrupt coordination between transcriptional and phenotypic stress responses in pathogenic bacteria

PA Jensen, Z Zhu, T van Opijnen - Cell reports, 2017 - cell.com
Bacterial genes that change in expression upon environmental disturbance have commonly
been seen as those that must also phenotypically matter. However, several studies suggest …

[图书][B] Stress and environmental regulation of gene expression and adaptation in bacteria

FJ De Bruijn - 2016 - books.google.com
Bacteria in various habitats are subject to continuously changing environmental conditions,
such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication …