Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria
D Nguyen, A Joshi-Datar, F Lepine, E Bauerle… - Science, 2011 - science.org
Bacteria become highly tolerant to antibiotics when nutrients are limited. The inactivity of
antibiotic targets caused by starvation-induced growth arrest is thought to be a key …
antibiotic targets caused by starvation-induced growth arrest is thought to be a key …
Nonoptimal microbial response to antibiotics underlies suppressive drug interactions
Suppressive drug interactions, in which one antibiotic can actually help bacterial cells to
grow faster in the presence of another, occur between protein and DNA synthesis inhibitors …
grow faster in the presence of another, occur between protein and DNA synthesis inhibitors …
Hormetic dose responses induced by antibiotics in bacteria: A phantom menace to be thoroughly evaluated to address the environmental risk and tackle the antibiotic …
I Iavicoli, L Fontana, E Agathokleous… - Science of the Total …, 2021 - Elsevier
The environmental contamination of antibiotics caused by their over or inappropriate use is
a major issue for environmental and human health since it can adversely impact the …
a major issue for environmental and human health since it can adversely impact the …
[PDF][PDF] Bacterial stress response
EZ Ron - The prokaryotes, 2006 - ndl.ethernet.edu.et
Most bacteria live in a dynamic environment where temperature, availability of nutrients, and
presence of various chemicals vary. Quick adaptation to these environmental changes is …
presence of various chemicals vary. Quick adaptation to these environmental changes is …
The SOS response increases bacterial fitness, but not evolvability, under a sublethal dose of antibiotic
C Torres-Barceló, M Kojadinovic… - … of the Royal …, 2015 - royalsocietypublishing.org
Exposure to antibiotics induces the expression of mutagenic bacterial stress–response
pathways, but the evolutionary benefits of these responses remain unclear. One possibility is …
pathways, but the evolutionary benefits of these responses remain unclear. One possibility is …
Short-and long-term transcriptomic responses of Escherichia coli to biocides: a systems analysis
B Merchel Piovesan Pereira, X Wang… - Applied and …, 2020 - Am Soc Microbiol
The mechanisms of the bacterial response to biocides are poorly understood, despite their
broad application. To identify the genetic basis and pathways implicated in the biocide …
broad application. To identify the genetic basis and pathways implicated in the biocide …
Variation in stress responses within a bacterial species and the indirect costs of stress resistance
Bacteria can exhibit high levels of resistance to one or more environmental stresses such as
temperature, osmolarity, radiation, pH, starvation, as well as resistance to noxious chemicals …
temperature, osmolarity, radiation, pH, starvation, as well as resistance to noxious chemicals …
Evolutionary potential, cross‐stress behavior and the genetic basis of acquired stress resistance in Escherichia coli
M Dragosits, V Mozhayskiy… - Molecular systems …, 2013 - embopress.org
Bacterial populations have a remarkable capacity to cope with extreme environmental
fluctuations in their natural environments. In certain cases, adaptation to one stressful …
fluctuations in their natural environments. In certain cases, adaptation to one stressful …
Nonessential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress
A Babosan, L Fruchard, E Krin, A Carvalho, D Mazel… - …, 2022 - academic.oup.com
Antimicrobial resistance develops as a major problem in infectious diseases treatment.
While antibiotic resistance mechanisms are usually studied using lethal antibiotic doses …
While antibiotic resistance mechanisms are usually studied using lethal antibiotic doses …
Gene expression variability underlies adaptive resistance in phenotypically heterogeneous bacterial populations
The root cause of the antibiotic resistance crisis is the ability of bacteria to evolve resistance
to a multitude of antibiotics and other environmental toxins. The regulation of adaptation is …
to a multitude of antibiotics and other environmental toxins. The regulation of adaptation is …