Pharmacogenetics in clinical practice: considerations for testing

S Constable, MR Johnson… - Expert Review of …, 2006 - Taylor & Francis
Pharmacogenetics is a rapidly evolving field that will undoubtedly lead to the development
of pharmacogenetic tests. Such tests will need to be assimilated into healthcare systems, but …

Evidence required to demonstrate clinical utility of pharmacogenetic testing: the debate continues

NK Gillis, F Innocenti - Clinical Pharmacology & Therapeutics, 2014 - Wiley Online Library
Pharmacogenetics is an area of research that has potential to greatly benefit patients.
However, the routine use of diagnostic pharmacogenetic testing to inform treatment …

[HTML][HTML] Just how feasible is pharmacogenetic testing in the primary healthcare setting?

JJ Swen, HJ Guchelaar - Pharmacogenomics, 2012 - Taylor & Francis
Medical Association that within a decade “… many primary care clinicians will become
practitioners of genomic medicine…”[1]. In the following years, pharmacogenetics was …

Pharmacogenetic tests: the need for a level playing field

M Pirmohamed, DA Hughes - Nature reviews Drug discovery, 2013 - nature.com
The delivery of more personalized medicinecould be accelerated by addressing the
substantial differences in the level of evidence required for the inclusion of pharmacogenetic …

Navigating the labyrinth of pharmacogenetic testing: a guide to test selection

CA Bousman, H Zierhut… - Clinical Pharmacology & …, 2019 - Wiley Online Library
Numerous commercial laboratories offer clinical pharmacogenetic testing in the United
States and abroad. With many pharmacogenetic testing choices, healthcare providers (eg …

From bench to bedside: a diagnostics framework for pharmacogenetics research

DA Katz - Molecular genetics and metabolism, 2002 - Elsevier
Although many genetic variants have been associated with differential drug responses, a
very limited number of pharmacogenetic tests have entered common clinical practice …

Clinical application of pharmacogenetics: focusing on practical issues

MT Chang, JJ McCarthy, J Shin - Pharmacogenomics, 2015 - Taylor & Francis
Recent large-scale genetic-based studies have transformed the field of pharmacogenetics to
identify, characterize and leverage genetic information to inform patient care. Genetic testing …

Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines Part 1

S Kim, YM Yun, IS Kim, SH Song… - Laboratory …, 2016 - synapse.koreamed.org
Pharmacogenetics is a rapidly evolving field, and the number of pharmacogenetic tests for
clinical use is steadily increasing. However, incorrect or inadequate implementation and use …

Pharmacogenetics: from discovery to patient care

J Shin, SR Kayser, TY Langaee - American Journal of Health …, 2009 - academic.oup.com
Purpose. The basic concepts of pharmacogenetics, pharmacogenetic study approaches,
factors to consider when applying pharmacogenetic discoveries to patient care, and …

Clinical pharmacy consultation for pharmacogenetic testing

J Shin, SR Kayser - Personalized Medicine, 2009 - Taylor & Francis
The clinical application of pharmacogenetic testing will help to bring personalized medicine
into clinical practice. Due to the complex process involved in delivering pharmacogenetic …