[HTML][HTML] Reactive oxygen species mediate bactericidal killing elicited by carbon monoxide-releasing molecules

AFN Tavares, M Teixeira, CC Romão, JD Seixas… - Journal of Biological …, 2011 - ASBMB
CO-releasing molecules (CO-RMs) were previously shown by us to be more potent
bactericides than CO gas. This suggests a mechanism of action for CO-RM, which either …

A role for reactive oxygen species in the antibacterial properties of carbon monoxide-releasing molecules

AFN Tavares, LS Nobre… - FEMS microbiology letters, 2012 - academic.oup.com
Carbon monoxide-releasing molecules (CO-RMs) are, in general, transition metal carbonyl
complexes that liberate controlled amounts of CO. In animal models, CO-RMs have been …

Recent advances on carbon monoxide releasing molecules for antibacterial applications

J Cheng, J Hu - ChemMedChem, 2021 - Wiley Online Library
Carbon monoxide (CO) has been known as an endogenous signaling molecule in addition
to an air pollutant. It plays a critical role in many physiological and pathological processes …

CORM‐A1: a new pharmacologically active carbon monoxide‐releasing molecule

R Motterlini, P Sawle, S Bains, J Hammad… - The FASEB …, 2005 - Wiley Online Library
Carbon monoxide (CO) is emerging as an important and versatile mediator of physiological
processes to the extent that treatment of animals with exogenous CO gas has beneficial …

Antibacterial effects of carbon monoxide

J Louise Wilson, HE Jesse, RK Poole… - Current …, 2012 - ingentaconnect.com
Carbon monoxide (CO) is a colourless and odourless gas that has long been considered as
a potent respiratory poison. Recent advances have demonstrated its production by haem …

Antimicrobial action of carbon monoxide-releasing compounds

LS Nobre, JD Seixas, CC Romao… - Antimicrobial agents and …, 2007 - Am Soc Microbiol
Carbon monoxide (CO) is endogenously produced in the human body, mainly from the
oxidation of heme catalyzed by heme oxygenase (HO) enzymes. The induction of HO and …

Development of triggerable, trackable, and targetable carbon monoxide releasing molecules

LS Lazarus, AD Benninghoff… - Accounts of chemical …, 2020 - ACS Publications
Conspectus Carbon monoxide (CO) is a gaseous signaling molecule produced in humans
via the breakdown of heme in an O2-dependent reaction catalyzed by heme oxygenase …

[HTML][HTML] Redox and catalase-like activities of four widely used carbon monoxide releasing molecules (CO-RMs)

Z Yuan, X Yang, B Wang - Chemical Science, 2021 - pubs.rsc.org
The pathophysiological roles of the endogenous signaling molecule, carbon monoxide
(CO), have been extensively studied and validated in cell culture and animal models …

Carbon monoxide in biology and microbiology: surprising roles for the “Detroit perfume”

KS Davidge, R Motterlini, BE Mann, JL Wilson… - Advances in microbial …, 2009 - Elsevier
Carbon monoxide (CO) is a colorless, odorless gas with a reputation for being an
anthropogenic poison; there is extensive documentation of the modes of human exposure …

Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology

N Bauer, Z Yuan, X Yang, B Wang - Biochemical Pharmacology, 2023 - Elsevier
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …