Carbon monoxide (CO), which is formed in mammalian cells through the oxidation of haem
by the enzyme haem oxygenase, actively participates in the regulation of key intracellular …

Complexes of the general formula fac-[Ru (CO) 3L3] 2+, namely CORM-2 and CORM-3,
have been successfully used as experimental CO releasing molecules (CO-RMs) but their …

Aims: Carbon monoxide is a respiratory poison and gaseous signaling molecule. Although
CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in …

Carbon monoxide (CO), like nitric oxide (NO), is an essential signalling molecule in humans.
It is active in the cardiovascular system as a vasodilator. In addition, CO possesses anti …

Several metal-based carbon monoxide-releasing molecules (CORMs) are active CO donors
with established antibacterial activity. Among them, CORM conjugates with azole antibiotics …

Ruthenium-based CO-releasing molecules (CO-RMs), CORM-2 and CORM-3, have been
widely used as surrogates of CO for studying its biological effects in vitro and in vivo with …

Although toxic when inhaled in high concentrations, the gas carbon monoxide (CO) is
endogenously produced in mammals, and various beneficial effects are reported. For …

The cytoprotective properties of carbon monoxide (CO) gas and CO‐releasing molecules
(CORM s) are well established. Despite promising pre‐clinical results, little attention has …

The development of carbon‐monoxide‐releasing molecules (CORMs) as pharmaceutical
agents represents an attractive and safer alternative to administration of gaseous CO. Most …

The surprising discovery of carbon monoxide (CO) as a signaling molecule in mammalian
physiology has recently raised interest in this toxic gas among researchers in biochemical …