Towards improved therapeutic CORMs: understanding the reactivity of CORM-3 with proteins
T Santos-Silva, A Mukhopadhyay… - Current medicinal …, 2011 - ingentaconnect.com
The biological role of carbon monoxide (CO) has completely changed in the last decade.
Beyond its widely feared toxicity, CO has revealed a very important biological activity as a …
Beyond its widely feared toxicity, CO has revealed a very important biological activity as a …
A manganese photosensitive tricarbonyl molecule [Mn(CO)3(tpa-κ3N)]Br enhances antibiotic efficacy in a multi-drug-resistant Escherichia coli
N Rana, HE Jesse, M Tinajero-Trejo… - …, 2017 - microbiologyresearch.org
Carbon monoxide-releasing molecules (CORMs) are a promising class of new
antimicrobials, with multiple modes of action that are distinct from those of standard …
antimicrobials, with multiple modes of action that are distinct from those of standard …
Carbon monoxide is a poison… to microbes! CO as a bactericidal molecule
BY Chin, LE Otterbein - Current opinion in pharmacology, 2009 - Elsevier
Inflammation and immunity result in a wide range of disease processes, including chronic
obstructive pulmonary disease, ischemia–reperfusion injury, atherosclerosis, vascular …
obstructive pulmonary disease, ischemia–reperfusion injury, atherosclerosis, vascular …
[HTML][HTML] Gasotransmitters, poisons, and antimicrobials: it's a gas, gas, gas!
M Tinajero-Trejo, HE Jesse, RK Poole - F1000prime reports, 2013 - ncbi.nlm.nih.gov
We review recent examples of the burgeoning literature on three gases that have major
impacts in biology and microbiology. NO, CO and H 2 S are now co-classified as …
impacts in biology and microbiology. NO, CO and H 2 S are now co-classified as …
Chemistry and biological activities of CO-releasing molecules (CORMs) and transition metal complexes
R Alberto, R Motterlini - Dalton Transactions, 2007 - pubs.rsc.org
The advent of CO as a small molecule that, in addition to NO, elicits essential biological
functions has initiated the search for compounds and complexes capable of releasing CO in …
functions has initiated the search for compounds and complexes capable of releasing CO in …
Bioactive properties of iron-containing carbon monoxide-releasing molecules
P Sawle, J Hammad, IJS Fairlamb, B Moulton… - … of Pharmacology and …, 2006 - ASPET
Carbon monoxide-releasing molecules (CO-RMs) are compounds capable of delivering
controlled amounts of CO within a cellular environment. Ruthenium-based carbonyls …
controlled amounts of CO within a cellular environment. Ruthenium-based carbonyls …
Strategies toward organic carbon monoxide prodrugs
Conspectus Carbon monoxide is widely acknowledged as an important gasotransmitter in
the mammalian system with importance on par with that of nitric oxide. It has also been firmly …
the mammalian system with importance on par with that of nitric oxide. It has also been firmly …
CO–metal interaction: vital signaling from a lethal gas
J Boczkowski, JJ Poderoso, R Motterlini - Trends in biochemical sciences, 2006 - cell.com
The past few years have witnessed intense research into the biological significance of
carbon monoxide (CO) as an essential signaling mediator in cells and tissues. To transduce …
carbon monoxide (CO) as an essential signaling mediator in cells and tissues. To transduce …
Generation of carbon monoxide releasing molecules (CO-RMs) as drug candidates for the treatment of acute liver injury: targeting of CO-RMs to the liver
AR Marques, L Kromer, DJ Gallo, N Penacho… - …, 2012 - ACS Publications
The discovery of the biological effects of carbon monoxide (CO) in recent years strongly
suggests that CO could find applications as a therapeutic agent. CO is a highly toxic gas …
suggests that CO could find applications as a therapeutic agent. CO is a highly toxic gas …
Feedback response to selective depletion of endogenous carbon monoxide in the blood
H Kitagishi, S Minegishi, A Yumura… - Journal of the …, 2016 - ACS Publications
The physiological roles of endogenous carbon monoxide (CO) have not been fully
understood because of the difficulty in preparing a loss-of-function phenotype of this …
understood because of the difficulty in preparing a loss-of-function phenotype of this …