Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …

Antibiotic and ROS linkage questioned | Nature Biotechnology Skip to main content Thank you
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The CO-releasing ability of a diverse library of primary metal carbonyl complexes has been
assessed using a deoxymyoglobin-carbonmonoxymyglobin assay. A wide spectrum of rates …

Carbon monoxide (CO) is produced in mammalian cells during heme metabolism and
serves as an important signaling messenger. Here we report the bioactive properties of …

As a water-soluble carbon monoxide-releasing molecule, CORM-3 is widely used as a CO
donor to study CO in the life system. CORM-3 can also replace gaseous CO as a therapeutic …

The endogenously produced oxidant hypothiocyanous acid (HOSCN) inhibits and kills
pathogens but paradoxically is well tolerated by mammalian host tissue. Mammalian high …

Observations of the effects of carbon monoxide (CO) on mammalian systems have been
known for thousands of years. To be sure, CO is deadly under certain conditions and …

Reactive oxygen species (ROS) produced as a secondary effect of bactericidal antibiotics
are hypothesized to play a role in killing bacteria. If correct, ROS may play a role in …

Carbon monoxide as an endogenous signaling molecule exhibits pharmacological efficacy
in various animal models of organ injury. To address the difficulty in using CO gas as a …

Conspectus The recent surprising discovery of the beneficial effects of carbon monoxide
(CO) in mammalian physiology has drawn attention toward site-specific delivery of CO to …