Design and evaluation of bilayered buccal film preparations for local administration of lidocaine hydrochloride

M Preis, C Woertz, K Schneider, J Kukawka… - European Journal of …, 2014 - Elsevier
Bilayered oromucosal film preparations (buccal films) offer a promising way to enable drug
administration via the oral cavity. Adding a non-soluble or slowly eroding/dissolving backing …

Bilayered buccal films as child-appropriate dosage form for systemic administration of propranolol

A Abruzzo, FP Nicoletta, F Dalena, T Cerchiara… - International journal of …, 2017 - Elsevier
Buccal mucosa has emerged as an attractive site for systemic administration of drug in
paediatric patients. This route is simple and non-invasive, even if the saliva wash-out effect …

Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery

C Remuñán-López, A Portero, JL Vila-Jato… - Journal of controlled …, 1998 - Elsevier
This paper describes the preparation of new buccal bilayered devices comprising a drug-
containing mucoadhesive layer and a drug-free backing layer, by two different methods …

Oromucosal multilayer films for tailor-made, controlled drug delivery

S Lindert, J Breitkreutz - Expert opinion on drug delivery, 2017 - Taylor & Francis
Introduction: The oral mucosa has recently become increasingly important as an alternative
administration route for tailor-made, controlled drug delivery. Oromucosal multilayer films …

[HTML][HTML] Preparation and evaluation of buccoadhesive films of atenolol

BK Satishbabu, BP Srinivasan - Indian journal of pharmaceutical …, 2008 - ncbi.nlm.nih.gov
This paper describes the preparation of new bilayered device comprising a drug containing
mucoadhesive layer and a drug free backing layer. Bilaminated films were produced by a …

Development of polymer film dosage forms of lidocaine for buccal administration: I. Penetration rate and release rate

H Okamoto, H Taguchi, K Iida, K Danjo - Journal of controlled release, 2001 - Elsevier
We examined the penetration rate of lidocaine (LC) through excised oral mucosa from
hamster cheek pouch and the in vitro release rate of LC from film dosage forms with …

Formulation of monolayered films with drug and polymers of opposing solubilities

VA Perumal, D Lutchman, I Mackraj… - International journal of …, 2008 - Elsevier
The aim of this study was to prepare and characterise monolayered multipolymeric films
(MMFs) comprising of a hydrophilic drug (Propranolol HCl)(PHCl) and polymers of opposing …

In vitro techniques to evaluate buccal films

AB Nair, R Kumria, S Harsha, M Attimarad… - Journal of Controlled …, 2013 - Elsevier
Extensive research on transmucosal drug delivery in the past few decades has resulted in
the clinical application of several drug molecules through the buccal route. Interestingly …

Mucoadhesive multiparticulate patch for the intrabuccal controlled delivery of lidocaine

C Cavallari, A Fini, F Ospitali - European Journal of Pharmaceutics and …, 2013 - Elsevier
The aim of the present study was to prepare and evaluate patches for the controlled release
of lidocaine in the oral cavity. Mucoadhesive buccal patches, containing 8mg/cm2 lidocaine …

Layer-by-layer self-assembly films for buccal drug delivery: The effect of polymer cross-linking

B Pilicheva, Y Uzunova, I Bodurov, A Viraneva… - Journal of Drug Delivery …, 2020 - Elsevier
The goal of this study was the preparation of multilayer polyectrolyte films intended for
buccal delivery of benzydamine (BZ). Another important issue was to evaluate the effect of …