Molecular mechanisms of vascular effects of high‐density lipoprotein: alterations in cardiovascular disease

C Besler, TF Lüscher, U Landmesser - EMBO molecular medicine, 2012 - embopress.org
Low high‐density lipoprotein (HDL)‐cholesterol levels are associated with an increased risk
of coronary artery disease (CAD) and myocardial infarction, which has triggered the …

Atheroprotective effects of high-density lipoproteins

G Assmann, JR Nofer - Annual review of medicine, 2003 - annualreviews.org
Observational studies provide overwhelming evidence that a low high-density lipoprotein
(HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and …

High density lipoproteins and endothelial functions: mechanistic insights and alterations in cardiovascular disease1

M Riwanto, U Landmesser - Journal of lipid research, 2013 - ASBMB
Prospective population studies in the primary prevention setting have shown that reduced
plasma levels of HDL cholesterol are associated with an increased risk of coronary disease …

Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part I

PK Shah, S Kaul, J Nilsson, B Cercek - Circulation, 2001 - Am Heart Assoc
crease in HDL, whereas hepatic overexpression of scavenger receptor (SR)-BI with gene
transfer reduces atherosclerosis, despite a major reduction in HDL levels. 47, 48 …

High-density lipoprotein: is it always atheroprotective?

BJ Ansell, GC Fonarow, AM Fogelman - Current atherosclerosis reports, 2006 - Springer
High-density lipoproteins (HDLs) are appropriately recognized for their many
atheroprotective functions, including reverse cholesterol transport, as well as antioxidant …

The role of high-density lipoprotein cholesterol in the prevention and possible treatment of cardiovascular diseases

BG Choi, G Vilahur, D Yadegar… - Current molecular …, 2006 - ingentaconnect.com
Despite significant progress in the management of atherosclerosis and its resultant
complications, cardiovascular disease remains the principal cause of death in the world. The …

The anti inflammatory effects of high density lipoproteins

AJ Murphy, JPF Chin-Dusting… - Current medicinal …, 2009 - ingentaconnect.com
It is well recognised that increased levels of high density lipoprotein (HDL) protect against
atherosclerosis and correlate with improved prognosis for vascular disease associated …

HDL in atherosclerotic cardiovascular disease: in search of a role

M Casula, O Colpani, S Xie, AL Catapano, A Baragetti - Cells, 2021 - mdpi.com
For a long time, high-density lipoprotein cholesterol (HDL-C) has been regarded as a
cardiovascular disease (CVD) protective factor. Recently, several epidemiological studies …

HDL-mediated mechanisms of protection in cardiovascular disease

A Kontush - Cardiovascular research, 2014 - academic.oup.com
Low plasma levels of HDL-cholesterol (HDL-C) represent a strong and independent risk
factor for cardiovascular disease. HDL particles display a wide spectrum of atheroprotective …

High-density lipoprotein-mediated anti-atherosclerotic and endothelial-protective effects: a potential novel therapeutic target in cardiovascular disease

C Besler, K Heinrich, M Riwanto… - Current …, 2010 - ingentaconnect.com
Reduced levels of high-density lipoprotein cholesterol (HDL) are associated with a
substantially increased risk of coronary disease and cardiovascular events. Furthermore …