It is a truth universally acknowledged that in order to popularize a new epidemiological
technique, one has to invent a suitably exciting sounding name for it. The term 'Mendelian …

Finding individual-level data for adequately-powered Mendelian randomization analyses
may be problematic. As publicly-available summarized data on genetic associations with …

Mendelian Randomization: Methods For Causal Inference Using Genetic Variants provides
thorough coverage of the methods and practical elements of Mendelian randomization …

Abstract Background Factorial Mendelian randomization is the use of genetic variants to
answer questions about interactions. Although the approach has been used in applied …

Mendelian randomisation uses genetic variation as a natural experiment to investigate the
causal relations between potentially modifiable risk factors and health outcomes in …

Mendelian randomization (MR) studies are often described as naturally occurring
randomized trials in which genetic factors are randomly assigned by nature …

If homogeneity is not plausible (as is the case in many research settings), 10–12 another
option is to target a “local” average causal effect within a subset of the study population. 10 …

Introduction Instrumental variable (IV) methods have been used in econometrics for several
decades now, but have only recently been introduced into the epidemiologic research …

The methodology and application of Mendelian randomization to study causal mechanisms
in health and disease has developed dramatically over the past decade. New methods …

Objective Mendelian randomization is a popular technique for assessing and estimating the
causal effects of risk factors. If genetic variants which are instrumental variables for a risk …