Background: Stroke is a major global burden with significant morbidity, mortality, and long-
term disability. Acute ischemic stroke (AIS) is a stressful condition causing stimulation of the …

Background Early prediction of outcome is important for allocation of therapeutic strategies.
Endocrine alterations of the hypothalamus–pituitary–axis are one of the first stress-induced …

Background: Stroke is the second commonest reason of mortality worldwide and a major
cause of long term disability. Early prediction of outcome is important for allocation of …

Background: The stress response that occurs after the event of acute stroke causes the
activation of the hypothalamopituitaryadrenal (HPA) axis. Certain studies have found that …

Studies in non-stroke patients have shown an association between dysregulation of the
hypothalamic–pituitary–adrenal axis and morbidity and mortality. We conducted a …

Background: Acute Ischemic Stroke (AIS) represents an economic challenge for health
systems all over the globe. Changes of neuroactive steroids have been found in different …

Objective. Elevated cortisol levels are associated with confusion and poor outcome after
stroke. Dehydroepiandrosterone sulphate (DS), the most abundant adrenal androgen may …

Background: Activation of the hypothalamo-pituitary-adrenal axis has been shown in acute
ischemic stroke. Some recent studies suggest that serum cortisol level may have prognostic …

Background: The adrenal glucocorticoid stress response in humans causes catabolism,
increasing blood glucose and heart rate, and possibly potentiates ischaemic damage to …

Hypercortisolemia is thought to be a marker of the stress response following stroke. The aim
of this study was to investigate the prevalence and prognostic significance of …