Overgrowth disorders comprise a group of entities with a variable phenotypic spectrum
ranging from tall stature to isolated or lateralized overgrowth of body parts and or organs …

The overgrowth syndromes are important to diagnose, not just for accurate genetic
counseling, but also for knowledge surrounding cancer surveillance and prognosis. There …

Abnormally excessive growth results from perturbation of a complex interplay of genetic,
epigenetic, and hormonal factors that orchestrate human growth. Overgrowth syndromes …

Overgrowth syndromes are a heterogeneous group of rare disorders characterized by
generalized or segmental excessive growth commonly associated with additional features …

In recent years, numerous overgrowth syndromes have been found to be caused by
pathogenic DNA sequence variants in “epigenes,” genes that encode proteins that function …

Genomic insights into growth and its disorders: an update : Current Opinion in Endocrinology,
Diabetes and Obesity Genomic insights into growth and its disorders: an update : Current …

Overgrowth Syndromes is a comprehensive clinical guide to the well-defined genetic
disorders (and others that are less well-defined) for which somatic overgrowth is a major …

Human overgrowth disorders are characterized by excessive prenatal and/or postnatal
growth of various tissues. These disorders often present with tall stature, macrocephaly …

Overgrowth syndromes, although rare, are diagnosed more frequently lately. Major
progress, such as the identification of genetic causes, has recently enhanced the delineation …

This introduction to the special issue of AJMG Part C: Overgrowth Syndromes updates the
current understanding of overgrowth syndromes. We clarify the terminology associated with …