A central step in the transfer of genetic information during bacterial conjugation of the
Escherichia coli F plasmid involves the formation of a protein-DNA complex, called the …

Bacterial conjugation is the process by which a single strand of a conjugative plasmid is
transferred from donor to recipient. For F plasmid, TraI, a relaxase or nickase, binds a single …

Conjugative DNA transfer is a highly conserved process for the direct transfer of DNA from a
donor to a recipient. The conjugative initiator proteins are key players in the DNA processing …

F plasmid‐mediated bacterial conjugation requires interactions between a relaxosome
component, TraM, and the coupling protein TraD, a hexameric ring ATPase that forms the …

The tra operon of the prototypical F plasmid and its relatives enables transfer of a copy of the
plasmid to other bacterial cells via the process of conjugation. Tra proteins assemble to form …

F plasmid conjugative transfer is initiated by the introduction of a site-and strand-specific
nick within the plasmid origin of transfer (oriT). Genetic studies have shown nick formation to …

Bacterial conjugation is an important source of genetic plasticity. The initiation complex for
conjugative transfer of transmissible plasmids—the relaxosome—is a specific DNA-protein …

The F factor traY gene product (TraYp) is a site‐specific DNA‐binding protein involved in
initiation of DNA transfer during bacterial conjugation. The sequence of TraYp exhibits a …

Bacteria commonly exchange genetic information by the horizontal transfer of conjugative
plasmids. In gram-negative conjugation, a relaxase enzyme is absolutely required to …

Relaxosomes are specific nucleoprotein structures involved in DNA‐processing reactions
during bacterial conjugation. In this work, we present evidence indicating that plasmid R388 …