Acute glucose and lactate metabolism are associated with cognitive recovery following traumatic brain injury
C Mannino, TC Glenn, DA Hovda… - Journal of …, 2018 - Wiley Online Library
Traumatic brain injury (TBI) is associated with acute cerebral metabolic crisis (ACMC).
ACMC‐related atrophy appears to be prominent in frontal and temporal lobes following …
ACMC‐related atrophy appears to be prominent in frontal and temporal lobes following …
Delayed glucose treatment improves cognitive function following fluid-percussion injury
ON Kokiko-Cochran, MP Michaels, RJ Hamm - Neuroscience Letters, 2008 - Elsevier
Experimental traumatic brain injury (TBI) results in marked neurochemical and metabolic
changes. Research has demonstrated that after the initial insult the brain undergoes an …
changes. Research has demonstrated that after the initial insult the brain undergoes an …
Statistical image analysis of cerebral glucose metabolism in patients with cognitive impairment following diffuse traumatic brain injury
T Kato, N Nakayama, Y Yasokawa… - Journal of …, 2007 - liebertpub.com
The aim of this study was to explore the regional cerebral glucose metabolism (rCM) in
patients with chronic stage traumatic brain injury (TBI) compared with normal controls. We …
patients with chronic stage traumatic brain injury (TBI) compared with normal controls. We …
Early metabolic crisis-related brain atrophy and cognition in traumatic brain injury
Traumatic brain injury often results in acute metabolic crisis. We recently demonstrated that
this is associated with chronic brain atrophy, which is most prominent in the frontal and …
this is associated with chronic brain atrophy, which is most prominent in the frontal and …
Cerebral metabolic dysfunction at the acute phase of traumatic brain injury correlates with long-term tissue loss
Following traumatic brain injury (TBI), cerebral metabolic dysfunction, characterized by an
elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor …
elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor …
Dissociation of cerebral glucose metabolism and level of consciousness during the period of metabolic depression following human traumatic brain injury
M Bergsneider, DA Hovda, SM Lee, DF Kelly… - Journal of …, 2000 - liebertpub.com
Utilizing [18F] fluorodeoxyglucose positron emission tomography (FDG-PET), we studied the
correlation between CMRglc and the level of consciousness within the first month following …
correlation between CMRglc and the level of consciousness within the first month following …
Glucose administration after traumatic brain injury improves cerebral metabolism and reduces secondary neuronal injury
N Moro, S Ghavim, NG Harris, DA Hovda, RL Sutton - Brain research, 2013 - Elsevier
Clinical studies have indicated an association between acute hyperglycemia and poor
outcomes in patients with traumatic brain injury (TBI), although optimal blood glucose levels …
outcomes in patients with traumatic brain injury (TBI), although optimal blood glucose levels …
Functional anatomy of neuropsychological deficits after severe traumatic brain injury
Article Abstract—Background: Neurobehavioral disorders after severe traumatic brain injury
(TBI) are poorly correlated with focal lesions detected by structural neuroimaging techniques …
(TBI) are poorly correlated with focal lesions detected by structural neuroimaging techniques …
Delayed sodium pyruvate treatment improves working memory following experimental traumatic brain injury
N Moro, SS Ghavim, DA Hovda, RL Sutton - Neuroscience letters, 2011 - Elsevier
Prior work indicates that cerebral glycolysis is impaired following traumatic brain injury (TBI)
and that pyruvate treatment acutely after TBI can improve cerebral metabolism and is …
and that pyruvate treatment acutely after TBI can improve cerebral metabolism and is …
Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study
WM Brooks, CA Stidley, H Petropoulos… - Journal of …, 2000 - liebertpub.com
Proton magnetic resonance spectroscopy (1H-MRS) offers a unique insight into brain
cellular metabolism following traumatic brain injury (TBI). The aim of the present study was …
cellular metabolism following traumatic brain injury (TBI). The aim of the present study was …
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