Acute glucose and lactate metabolism are associated with cognitive recovery following traumatic brain injury

C Mannino, TC Glenn, DA Hovda… - Journal of …, 2018 - Wiley Online Library
Traumatic brain injury (TBI) is associated with acute cerebral metabolic crisis (ACMC).
ACMC‐related atrophy appears to be prominent in frontal and temporal lobes following …

Delayed glucose treatment improves cognitive function following fluid-percussion injury

ON Kokiko-Cochran, MP Michaels, RJ Hamm - Neuroscience Letters, 2008 - Elsevier
Experimental traumatic brain injury (TBI) results in marked neurochemical and metabolic
changes. Research has demonstrated that after the initial insult the brain undergoes an …

Statistical image analysis of cerebral glucose metabolism in patients with cognitive impairment following diffuse traumatic brain injury

T Kato, N Nakayama, Y Yasokawa… - Journal of …, 2007 - liebertpub.com
The aim of this study was to explore the regional cerebral glucose metabolism (rCM) in
patients with chronic stage traumatic brain injury (TBI) compared with normal controls. We …

Early metabolic crisis-related brain atrophy and cognition in traumatic brain injury

MJ Wright, DL McArthur, JR Alger, J Van Horn… - Brain imaging and …, 2013 - Springer
Traumatic brain injury often results in acute metabolic crisis. We recently demonstrated that
this is associated with chronic brain atrophy, which is most prominent in the frontal and …

Cerebral metabolic dysfunction at the acute phase of traumatic brain injury correlates with long-term tissue loss

A Bernini, S Magnoni, JP Miroz… - Journal of …, 2023 - liebertpub.com
Following traumatic brain injury (TBI), cerebral metabolic dysfunction, characterized by an
elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor …

Dissociation of cerebral glucose metabolism and level of consciousness during the period of metabolic depression following human traumatic brain injury

M Bergsneider, DA Hovda, SM Lee, DF Kelly… - Journal of …, 2000 - liebertpub.com
Utilizing [18F] fluorodeoxyglucose positron emission tomography (FDG-PET), we studied the
correlation between CMRglc and the level of consciousness within the first month following …

Glucose administration after traumatic brain injury improves cerebral metabolism and reduces secondary neuronal injury

N Moro, S Ghavim, NG Harris, DA Hovda, RL Sutton - Brain research, 2013 - Elsevier
Clinical studies have indicated an association between acute hyperglycemia and poor
outcomes in patients with traumatic brain injury (TBI), although optimal blood glucose levels …

Functional anatomy of neuropsychological deficits after severe traumatic brain injury

A Fontaine, P Azouvi, P Remy, B Bussel, Y Samson - Neurology, 1999 - AAN Enterprises
Article Abstract—Background: Neurobehavioral disorders after severe traumatic brain injury
(TBI) are poorly correlated with focal lesions detected by structural neuroimaging techniques …

Delayed sodium pyruvate treatment improves working memory following experimental traumatic brain injury

N Moro, SS Ghavim, DA Hovda, RL Sutton - Neuroscience letters, 2011 - Elsevier
Prior work indicates that cerebral glycolysis is impaired following traumatic brain injury (TBI)
and that pyruvate treatment acutely after TBI can improve cerebral metabolism and is …

Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study

WM Brooks, CA Stidley, H Petropoulos… - Journal of …, 2000 - liebertpub.com
Proton magnetic resonance spectroscopy (1H-MRS) offers a unique insight into brain
cellular metabolism following traumatic brain injury (TBI). The aim of the present study was …