MicroRNAs (miRNAs) are short endogenously expressed RNAs that have the potential to
regulate the expression of any RNA. This potential has led to the publication of several …

A large number of miRNAs have recently been discovered in plants and animals.
Development of reverse genetic approaches that act to inhibit microRNA function would …

Little is known about miRNA decay. A target-directed miRNA degradation mechanism
(TDMD) has been suggested, but further investigation on endogenous targets is necessary …

MicroRNAs (miRNAs) are endogenously encoded small noncoding RNAs, derived by
processing of short RNA hairpins, that can inhibit the translation of mRNAs bearing partially …

MicroRNAs (miRNAs) are abundant regulatory RNAs involved in the regulation of many key
biological processes. Recent advances in understanding the mechanism of RNA …

microRNAs (miRNAs) silence gene expression by suppressing protein production and/or by
promoting mRNA decay. To elucidate how silencing is accomplished, we screened an RNA …

MicroRNAs (miRNA) comprise an abundant class of small noncoding RNAs that act as
important posttranscriptional regulators of gene expression. Accumulating evidence …

The miRNA mimic technology (miR-Mimic) is an innovative approach for gene silencing.
This approach is to generate nonnatural double-stranded miRNA-like RNA fragments. Such …

MicroRNAs (miRNAs) are a class of short non-coding RNAs with posttranscriptional
regulatory functions. To date, more than 600 human miRNAs have been experimentally …

Recent studies have shown that microRNA (miRNA) regulates gene expression by
repressing translation or directing sequence-specific degradation of complementary mRNA …