Although eukaryotic cells use RNA silencing to defend against transposons and pathogens,
they also employ these pathways to regulate the expression of their own genes. Recent …

MicroRNAs (miRNAs) are a class of small regulatory RNAs that are thought to regulate the
expression of as many as one-third of all human messenger RNAs (mRNAs). miRNAs are …

MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways.
These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in …

MicroRNAs are post-transcriptional regulators that control mRNA stability and the translation
efficiency of their target genes. Mature microRNAs are approximately 22-nucleotide in …

MicroRNAs (miRNAs) are believed to play important roles in developmental and other
cellular processes by hybridizing to complementary target mRNA transcripts. This results in …

MicroRNAs (miRNAs) are small non-coding RNA molecules of 21–23 nucleotides that
control gene expression at the post-transcriptional level. They have been shown to play a …

Despite extensive research, the sequence features affecting microRNA-mediated regulation
are not well understood, limiting our ability to predict gene expression levels in both native …

Summary MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of
interfering with intracellular messenger RNAs (mRNAs) that contain either complete or …

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used
extensively to study the functions and mechanisms of endogenous miRNAs. However, it …

MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with
intracellular mRNAs that contain partial complementarity, are useful for the design of new …