Multilevel regulation of gene expression by microRNAs

EV Makeyev, T Maniatis - Science, 2008 - science.org
MicroRNAs (miRNAs) are∼ 22-nucleotide-long noncoding RNAs that normally function by
suppressing translation and destabilizing messenger RNAs bearing complementary target …

Functional conservation of both CDS-and 3′-UTR-located microRNA binding sites between species

G Liu, R Zhang, J Xu, CI Wu, X Lu - Molecular biology and …, 2015 - academic.oup.com
MicroRNAs (miRNAs) mediate gene regulation posttranscriptionally through pairing of their
seed (2–7 nt) to 3′-untranslated regions (3′-UTRs) or coding regions (coding sequences …

[HTML][HTML] The non-canonical aspects of microRNAs: many roads to gene regulation

CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

MicroRNA: potential for cancer detection, diagnosis, and prognosis

JV Tricoli, JW Jacobson - 2007 - AACR
The Cancer Diagnosis Program of the National Cancer Institute sponsored a workshop
entitled ''MicroRNA: Potential for Cancer Detection, Diagnosis, and Prognosis''in Rockville …

MicroRNA genes are transcribed by RNA polymerase II

Y Lee, M Kim, J Han, KH Yeom, S Lee, SH Baek… - The EMBO …, 2004 - embopress.org
MicroRNAs (miRNAs) constitute a large family of noncoding RNAs that function as guide
molecules in diverse gene silencing pathways. Current efforts are focused on the regulatory …

miRNA goes nuclear

V Huang, LC Li - RNA biology, 2012 - Taylor & Francis
microRNAs (miRNAs), defined as 21–24 nucleotide non-coding RNAs, are important
regulators of gene expression. Initially, the functions of miRNAs were recognized as post …

MicroRNAs: key participants in gene regulatory networks

XS Ke, CM Liu, DP Liu, CC Liang - Current opinion in chemical biology, 2003 - Elsevier
microRNAs (miRNAs) are a newly identified and surprisingly large class of endogenous tiny
regulatory RNAs. They exhibit various expressional patterns and are highly conserved …

The role of miRNAs in progesterone action

DR Cochrane, NS Spoelstra, JK Richer - Molecular and cellular …, 2012 - Elsevier
Small non-coding RNAs termed microRNAs (miRNAs) are mediators of post-transcriptional
gene silencing and are involved in all aspects of cell biology. Progesterone receptors (PR) …

Targeting of microRNAs for therapeutics

J Stenvang, M Lindow, S Kauppinen - 2008 - portlandpress.com
miRNAs (microRNAs) comprise a class of small endogenous non-coding RNAs that post-
transcriptionally repress gene expression by base-pairing with their target mRNAs. Recent …

Functional aspects of animal microRNAs

AE Williams - Cellular and molecular life sciences, 2008 - Springer
MicroRNAs (miRNAs) are a recently discovered family of small regulatory molecules that
function by modulating protein production. There are approximately 500 known mammalian …