[PDF][PDF] SnapShot: unconventional miRNA functions
MicroRNAs (miRNAs) are synonymous with post-transcriptional repression of target genes.
A number of studies, however, have reported miRNAs functioning outside this paradigm …
A number of studies, however, have reported miRNAs functioning outside this paradigm …
Mechanistic insights into microRNA-mediated gene silencing
TF Duchaine, MR Fabian - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein
synthesis and exert a broad influence over development, physiology, adaptation, and …
synthesis and exert a broad influence over development, physiology, adaptation, and …
A guide to micro RNA‐mediated gene silencing
M Quévillon Huberdeau, MJ Simard - The FEBS journal, 2019 - Wiley Online Library
As an important regulator of gene expression in eukaryotes, micro RNA s (mi RNA s) have
been subject to extensive research to understand their pleiotropic roles in development and …
been subject to extensive research to understand their pleiotropic roles in development and …
Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs
RJ Lebbink, M Lowe, T Chan, H Khine, X Wang… - PloS one, 2011 - journals.plos.org
Since the discovery of RNAi and microRNAs more than 10 years ago, much research has
focused on the development of systems that usurp microRNA pathways to downregulate …
focused on the development of systems that usurp microRNA pathways to downregulate …
Lentivirus-mediated antagomir expression for specific inhibition of miRNA function
M Scherr, L Venturini, K Battmer… - Nucleic acids …, 2007 - academic.oup.com
Micro RNAs (miRNA) regulate gene expression by hybridization and recruitment of multi-
protein complexes to complementary mRNA target sequences. miRNA function can …
protein complexes to complementary mRNA target sequences. miRNA function can …
The impact of miRNA target sites in coding sequences and in 3′ UTRs
Z Fang, N Rajewsky - PloS one, 2011 - journals.plos.org
Animal miRNAs are a large class of small regulatory RNAs that are known to directly and
negatively regulate the expression of a large fraction of all protein encoding genes. The …
negatively regulate the expression of a large fraction of all protein encoding genes. The …
A novel class of microRNA-recognition elements that function only within open reading frames
MicroRNAs (miRNAs) are well known to target 3′ untranslated regions (3′ UTRs) in
mRNAs, thereby silencing gene expression at the post-transcriptional level. Multiple reports …
mRNAs, thereby silencing gene expression at the post-transcriptional level. Multiple reports …
[HTML][HTML] MicroRNAs: genomics, biogenesis, mechanism, and function
DP Bartel - cell, 2004 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 22 nt RNAs that can play important regulatory
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
The road toward microRNA therapeutics
AG Seto - The international journal of biochemistry & cell biology, 2010 - Elsevier
Within the last 15 years, microRNAs (miRNAs) have emerged as powerful regulators of gene
expression. Highly conserved, these small RNAs appear to regulate nearly every aspect of …
expression. Highly conserved, these small RNAs appear to regulate nearly every aspect of …