[HTML][HTML] Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs
RJ Lebbink, M Lowe, T Chan, H Khine, X Wang… - PloS one, 2011 - journals.plos.org
Since the discovery of RNAi and microRNAs more than 10 years ago, much research has
focused on the development of systems that usurp microRNA pathways to downregulate …
focused on the development of systems that usurp microRNA pathways to downregulate …
MicroRNAs: biogenesis, function and applications.
JH Chua, A Armugam, K Jeyaseelan - Current opinion in molecular …, 2009 - europepmc.org
MicroRNAs (miRNAs) belong to the group of non-coding, small RNAs (19 to 21 nucleotide-
long oligonucleotides) that are endogenously produced from their own genes. miRNAs …
long oligonucleotides) that are endogenously produced from their own genes. miRNAs …
Sequence requirements for micro RNA processing and function in human cells
Y Zeng, BR Cullen - Rna, 2003 - rnajournal.cshlp.org
Most eukaryotes encode a substantial number of small noncoding RNAs termed micro RNAs
(miRNAs). Previously, we have demonstrated that miR-30, a 22-nucleotide human miRNA …
(miRNAs). Previously, we have demonstrated that miR-30, a 22-nucleotide human miRNA …
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
Transfection of small RNAs (such as small interfering RNAs (siRNAs) and microRNAs
(miRNAs)) into cells typically lowers expression of many genes. Unexpectedly, increased …
(miRNAs)) into cells typically lowers expression of many genes. Unexpectedly, increased …
A rapid, quantitative assay for direct detection of microRNAs and other small RNAs using splinted ligation
PA Maroney, S Chamnongpol, F Souret, TW Nilsen - Rna, 2007 - rnajournal.cshlp.org
The discovery and characterization of microRNAs (miRNAs) and other families of short
RNAs has led to a rapid expansion of research directed at elucidating their expression …
RNAs has led to a rapid expansion of research directed at elucidating their expression …
Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
K Kasashima, Y Nakamura, T Kozu - Biochemical and biophysical research …, 2004 - Elsevier
MicroRNAs (miRNAs) are highly conserved small non-coding RNAs that regulate gene
expression through translational repression by base-pairing with partially complementary …
expression through translational repression by base-pairing with partially complementary …
IsomiRs: expanding the miRNA repression toolbox beyond the seed
MicroRNAs (miRNAs) are a class of small non-coding RNAs that play increasingly
appreciated roles in gene regulation. In animals, miRNAs silence gene expression by …
appreciated roles in gene regulation. In animals, miRNAs silence gene expression by …
MicroRNAs: critical regulators of development, cellular physiology and malignancy
JT Mendell - Cell cycle, 2005 - Taylor & Francis
MicroRNAs (miRNAs) are 18-24 nucleotide RNA molecules that regulate the stability or
translational efficiency of target mRNAs. These regulatory RNAs function by acting as …
translational efficiency of target mRNAs. These regulatory RNAs function by acting as …
Differential expression of components of the microRNA machinery during mouse organogenesis
MicroRNA (miRNA)-mediated gene silencing has recently emerged as a major mechanism
of gene expression regulation during development in a variety of species. Little is known …
of gene expression regulation during development in a variety of species. Little is known …
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
AM Cheng, MW Byrom, J Shelton… - Nucleic acids …, 2005 - academic.oup.com
Of the over 200 identified mammalian microRNAs (miRNAs), only a few have known
biological activity. To gain a better understanding of the role that miRNAs play in specific …
biological activity. To gain a better understanding of the role that miRNAs play in specific …